Objectives We have postulated that common changes in gene expression after treatment
with different therapeutic classes of psychotropic drugs contribute to their common …

Human death is a complex, time-governed phenomenon that leads to the irreversible
cessation of all bodily functions. Recent molecular and genetic studies have revealed …

Background There are no effective pharmacological treatments for sarcopenia. We aim to
identify potential therapeutic targets for sarcopenia by integrating various publicly available …

Copper is one of a handful of biologically necessary heavy metals that is also a common
environmental pollutant. Under normal conditions, copper ions are required for many key …

Powdery mildew disease (PMD) is caused by the obligate biotrophic fungus Microsphaera
diffusa Cooke & Peck (M. diffusa) and results in significant yield losses in soybean (Glycine …

Genomics is increasingly applied in breeding programmes for farmed fish and shellfish
species around the world. However, current applications do not include information on …

Understanding the intricate relationships between diseases is critical for both prevention
and recovery. However, there is a lack of suitable methodologies for exploring the …

The aim of this study is to enhance the extraction of informative features from complex data
through the application of topological data analysis (TDA) using novel topological …

Expression quantitative trait locus (eQTL) analysis is a useful tool to identify genetic loci that
are associated with gene expression levels. Large collaborative efforts such as the …

Gene expression of cells in the tissues is a heterogeneous and dynamic program across
space and time. Spatiotemporal transcriptomics technologies have emerged as transforming …