Bone remodeling is a continuous and dynamic process of bone formation and resorption to
maintain its integrity and homeostasis. Bone marrow is a source of various cell lineages …

Tumor biomarkers, the substances which are produced by tumors or the body's responses to
tumors during tumorigenesis and progression, have been demonstrated to possess critical …

Introduction Prostate cancer is a common cancer among male population. The aberrant
expression of histone modifiers has been identified as a potential driving force in numerous …

Mammalian switch/sucrose nonfermentable (mSWI/SNF) ATPase degraders have been
shown to be effective in enhancer-driven cancers by functioning to impede oncogenic …

DNA-targeted drugs constitute a specialized category of pharmaceuticals developed for
cancer treatment, directly influencing various cellular processes involving DNA. These drugs …

Epigenetic modifications play crucial roles in physiological processes, including cell
differentiation, proliferation, and death. Bromodomain/Brd-containing proteins (BCPs) …

Diagnosis and stratification of prostate cancer (PCa) patients using the prostate‐specific
antigen (PSA) test is challenging. Extracellular vesicles (EVs), as a new star of liquid biopsy …

Cancer etiology involves complex interactions between genetic and non-genetic factors,
with epigenetic mechanisms serving as key regulators at multiple stages of pathogenesis …

Abstract The Food and Drug Administration (FDA) has approved vorinostat, also called
Zolinza®, for its effectiveness in fighting cancer. This drug is a suberoyl-anilide hydroxamic …

Histones are the key protein components of the nucleosome, the basic unit of chromatin.
Histones undergo several posttranslational modifications (PTMs) that, together with DNA …