Characterizing regional drug delivery within the nasal airways

J Chen, WH Finlay, R Vehring… - Expert Opinion on Drug …, 2024 - Taylor & Francis
Introduction The nose has been receiving increased attention as a route for drug delivery. As
the site of deposition constitutes the first point of contact of the body with the drug …

Parameter characteristics in intranasal drug delivery: A key to targeting medications to the olfactory airspace

RM Sicard, DO Frank-Ito - Clinical Biomechanics, 2024 - Elsevier
Background The nose is a viable pathway for topical drug delivery to the olfactory cleft for
treatment of obstructive smell loss and nose-to-brain drug delivery. This study investigates …

健康人鼻腔及鼻咽腔颗粒沉降的生物力学研究

杨花, 孙东, 苏英锋, 孙秀珍, 于申, 唐媛媛 - 中国耳鼻咽喉头颈外科, 2024 - entbjb.com
目的建立健康人鼻腔及鼻咽腔有限元数值模型, 分析不同条件下鼻腔及鼻咽腔的颗粒沉降特征,
从生物力学角度探讨颗粒沉降的影响因素, 为临床鼻腔及鼻咽腔疾病的潜在诱发因素及经鼻腔给 …