The contribution of three-dimensional genome organization to physiological ageing is not well known. Here we show that large-scale chromatin reorganization distinguishes young …
Global urbanisation has occurred in tandem with population ageing, having implications on human cognitive health. Urban environmental factors such as air pollution are known risk …
The ELN gene encodes tropoelastin which is used to generate elastic fibers that insure proper tissue elasticity. Decreased amounts of elastic fibers and/or accumulation of bioactive …
Brain aging causes a wide variety of changes at molecular and cellular levels, leading to the decline of cognitive functions and increased vulnerability to neurodegenerative disorders …
M kahaer, D Aikeremu, H Wang, K Xu, ZG Sun - bioRxiv, 2024 - biorxiv.org
The aim of this study is to summarize and visualize the current state of research on the relationship between epigenetic age and cellular senescence over the past two decades …