Ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolution has
given rise to recombinant Omicron lineages that dominate globally (XBB. 1), as well as the …

Memory T cells form from the adaptive immune response to historic infections or
vaccinations. Some memory T cells have the potential to recognise unrelated pathogens like …

Abstract Measuring SARS-CoV-2-specific T cell responses is crucial to understanding an
individual's immunity to COVID-19. However, high inter-and intra-assay variability make it …

Background Functional T-cell responses are essential for virus clearance and long-term
protection after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

Mucosal vaccines can prevent viruses from infecting the respiratory mucosa, rather than only
curtailing infection and protecting against the development of disease symptoms. The SARS …

Background The emergence of SARS-CoV-2 variants has raised concerns about the
sustainability of vaccine-induced immunity. Little is known about the long-term humoral …

The immunoprotective components control COVID-19 disease severity, as well as long-term
adaptive immunity maintenance and subsequent reinfection risk discrepancies across initial …

Currently approved vaccines have been successful in preventing the severity of COVID-19
and hospitalization. These vaccines primarily induce humoral immune responses; however …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
respiratory distress condition known as COVID-19. This disease broadly affects several …

Abstract SARS-CoV-2-specific CD8+ T cells recognize conserved viral peptides and in the
absence of cross-reactive antibodies form an important line of protection against emerging …