Objectives. RA associates with significantly increased morbidity and mortality from
cardiovascular disease (CVD). This may be due to complex interactions between traditional …

Objective. It remains a matter of debate whether TNF-α antagonists have favourable effects
on the cardiovascular (CV) system. This systematic review evaluates the effect of TNF-α …

Background Arterial stiffness is an independent cardiovascular risk factor in hypertensive
individuals. Inflammation is associated with increased arterial stiffness and is implicated in …

Rheumatoid arthritis is characterized by early and accelerated atherosclerosis leading to
increased cardiovascular morbidity and mortality. Beyond traditional cardiovascular risk …

The pulse wave velocity (PWV), as an indicator of arterial distensibility, may play an
important role in the stratification of patients based on the cardiovascular risk. PWV inversely …

Objective. To determine the efficacy of methotrexate (MTX) with infliximab (IFX) compared
with MTX alone in the prevention of atherosclerosis and arterial stiffness in patients with …

Controlling inflammation with tumor necrosis factor (TNF) inhibitors in rheumatoid arthritis
(RA) patients is hypothesized to reduce their cardiovascular risk. We performed a systematic …

Objective Endothelial dysfunction and vasculopathy of the small and large vessels are
crucial pathogenic factors in systemic sclerosis (SSc). Accelerated atherosclerosis and …

OBJECTIVES: Connective tissue diseases involve characteristic inflammatory lesions in the
cardiovascular system, in addition to other systems. The involvement of the cardiovascular …

Rheumatoid arthritis (RA) is accompanied by long lasting inflammation, which may lead to
arterial dysfunction and premature aging of the arteries. The purpose of this clinical work …