MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review

MV Iorio, CM Croce - EMBO molecular medicine, 2012 - embopress.org
Early studies have shown how aberrantly expressed microRNAs are a hallmark of several
diseases like cancer. MicroRNA expression profiling was shown to be associated with …

Regulation of microRNA by circular RNA

S Singh, T Sinha, AC Panda - Wiley Interdisciplinary Reviews …, 2024 - Wiley Online Library
Circular (circ) RNAs have emerged as novel regulators of gene expression through various
mechanisms. However, most publications focus on functional circRNAs regulating target …

Zebrafish and Medaka: new model organisms for modern biomedical research

CY Lin, CY Chiang, HJ Tsai - Journal of biomedical science, 2016 - Springer
Although they are primitive vertebrates, zebrafish (Danio rerio) and medaka (Oryzias latipes)
have surpassed other animals as the most used model organisms based on their many …

The emerging function and mechanism of ceRNAs in cancer

Y Wang, J Hou, D He, M Sun, P Zhang, Y Yu, Y Chen - Trends in Genetics, 2016 - cell.com
Complex diseases, such as cancer, are often associated with aberrant gene expression at
both the transcriptional and post-transcriptional level. Over the past several years …

MicroRNA-143 regulates human osteosarcoma metastasis by regulating matrix metalloprotease-13 expression

M Osaki, F Takeshita, Y Sugimoto, N Kosaka… - Molecular therapy, 2011 - cell.com
Pulmonary metastases are the main cause of death in patients with osteosarcoma, however,
the molecular mechanisms of metastasis are not well understood. To detect lung metastasis …

MicroRNAs in vascular and metabolic disease

A Zampetaki, M Mayr - Circulation research, 2012 - Am Heart Assoc
Recent findings demonstrated the importance of microRNAs (miRNAs) in the vasculature
and the orchestration of lipid metabolism and glucose homeostasis. MiRNA networks …

Chondrocyte-Specific MicroRNA-140 Regulates Endochondral Bone Development and Targets Dnpep To Modulate Bone Morphogenetic Protein Signaling

Y Nakamura, JB Inloes, T Katagiri… - Molecular and cellular …, 2011 - Taylor & Francis
MicroRNAs (miRNAs) play critical roles in a variety of biological processes in diverse
organisms, including mammals. In the mouse skeletal system, a global reduction of miRNAs …

[HTML][HTML] Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells

MN Wosczyna, EEP Carbajal, MW Wagner, S Paredes… - Cell Stem Cell, 2021 - cell.com
Intramuscular fatty deposits, which are seen in muscular dystrophies and with aging,
negatively affect muscle function. The cells of origin of adipocytes constituting these fatty …

Differential microRNA expression, microRNA arm switching, and microRNA: long noncoding RNA interaction in response to salinity stress in soybean

C Li, W Nong, S Zhao, X Lin, Y Xie, MY Cheung, Z Xiao… - BMC genomics, 2022 - Springer
Background Soybean is a major legume crop with high nutritional and environmental values
suitable for sustainable agriculture. Noncoding RNAs (ncRNAs), including microRNAs …

MicroRNAs in ovarian carcinomas

N Dahiya, PJ Morin - Endocrine-related cancer, 2010 - erc.bioscientifica.com
The new incretin-based therapies, dipeptidyl peptidase-4 (DPP4) inhibitors and glucagon
like peptide 1 (GLP1) receptor agonists are widely used for the treatment of type 2 diabetes …