Targeted sequencing approach and its clinical applications for the molecular diagnosis of human diseases

XM Pei, MHY Yeung, ANN Wong, HF Tsang, ACS Yu… - Cells, 2023 - mdpi.com
The outbreak of COVID-19 has positively impacted the NGS market recently. Targeted
sequencing (TS) has become an important routine technique in both clinical and research …

Lophomonas as a respiratory pathogen—jumping the gun

A Mewara, GH Gile, B Mathison, H Zhao… - Journal of clinical …, 2024 - Am Soc Microbiol
Human infections with the protozoan Lophomonas have been increasingly reported in the
medical literature over the past three decades. Initial reports were based on microscopic …

[HTML][HTML] Clinical challenge of diagnosing non-ventilator hospital-acquired pneumonia and identifying causative pathogens: a narrative review

S Quarton, A Livesey, H Pittaway, A Adiga… - Journal of Hospital …, 2024 - Elsevier
Non-ventilated hospital-acquired pneumonia (NV-HAP) is associated with a significant
healthcare burden, arising from high incidence and associated morbidity and mortality …

[PDF][PDF] Metagenomic next-generation sequencing vs. conventional detection methods for detecting the pulmonary infections.

XQ Shi, L Tian, ZH Huang, WT Song… - European Review for …, 2023 - europeanreview.org
OBJECTIVE: The absence of proper pathogen treatment in the early stages can result in
missing out on treatment chances or the overuse of antibiotics, both of which are the primary …

Menstrual Blood as a Diagnostic Specimen for Human Papillomavirus Genotyping and Genital Tract Infection Using Next-Generation Sequencing as a Novel …

HF Tsang, YS Cheung, CSA Yu, CSS Chan, CBT Wong… - Diagnostics, 2024 - mdpi.com
Background: Menstrual blood (MB) is a convenient specimen type that can be self-collected
easily and non-invasively by women. This study assessed the potential application of MB as …

Delayed diagnosis of persistent Q fever: a case series from China

S Wang, K Xu, G Wang - BMC Infectious Diseases, 2024 - Springer
Background Q fever, caused by the zoonotic pathogen Coxiella burnetii, exhibits a
worldwide prevalence. In China, Q fever is not recognized as a notifiable disease, and the …

[HTML][HTML] Comparison of next-generation sequencing with traditional methods for pathogen detection in cases of lower respiratory tract infection at a community hospital …

Y Yang, X Zhu, Y Sun, K Qian, Z Liu - Medicine, 2022 - journals.lww.com
Lower respiratory tract infection (LRTI) is still a threat to human health. Metagenomics next-
generation sequencing (NGS) provides an efficient and unbiased way to identify LRTI …

Clinical characteristics of 15 patients with listeria meningitis in adult

H Qu, Y Wang, H Diao, G Ren, Z Wang, J Shang… - Heliyon, 2024 - cell.com
Objective To report and analyze the clinical characteristics of 15 patients with Listeria
meningitis in adult. Methods We reviewed the medical records of 15 patients with Listeria …

[PDF][PDF] 宏基因二代测序诊断中间普雷沃菌致肺脓肿1 例

艾志波, 刘汉臣, 杜军 - 大连医科大学学报, 2023 - journal.dmu.edu.cn
患者, 男, 52 岁. 因“发热4 d, 后背部疼痛2 d” 于2022 年1 月9 日入联勤保障部队第九七〇医院.
患者于4 日前受凉感冒后出现畏寒, 发热, 自测体温最高38℃, 偶有咳嗽, 咳少量黄痰, 无寒战 …

[HTML][HTML] Pneumonia caused by Enterococcus faecalis and tropical candida in a maintenance hemodialysis patient concomitant with COVID-19: A case report and …

X He, Y Wang, S Liu, X Li - Medicine: Case Reports and Study …, 2024 - journals.lww.com
Interventions: Following initial treatment with a wide range of antibiotics guided by blood and
sputum cultures, there was no improvement in the patient's health. Further examination of …