Anaphylaxis is an acute, potential life-threatening systemic allergic reaction that may have a
wide range of clinical manifestations. Severe anaphylaxis and/or the need for repeated …

Background There are increasing global data relating to prevalence of food allergy and food-
induced anaphylaxis; however, this is often based on surrogate measures of sensitization …

The true global scale of anaphylaxis remains elusive, because many episodes occur in the
community without presentation to health care facilities, and most regions have not yet …

This practice parameter update focuses on 7 areas in which there are new evidence and
new recommendations. Diagnostic criteria for anaphylaxis have been revised, and patterns …

Background A biphasic reaction is a potentially life-threatening recurrence of symptoms after
initial resolution of anaphylaxis without re-exposure to the trigger. The infrequent nature of …

Anaphylaxis is a severe hypersensitivity reaction that is rapid in onset and can result in
death. The pattern of an anaphylactic reaction can be uniphasic (or monophasic), biphasic …

Drug hypersensitivity reactions (DHR) constitute a major and common public health
problem, particularly in children. One of the most severe manifestations of DHR is …

Anaphylaxis is a dramatic expression of systemic allergy. The lifetime prevalence of
anaphylaxis is currently estimated at 0.05–2% in the USA and~ 3% in Europe. Several …

Background Epidemiologic data regarding biphasic reactions in children with anaphylaxis
are sparse. Objective To investigate the incidence and clinical predictors of biphasic …

Background The biphasic reaction is a feared complication of anaphylaxis management in
the emergency department (ED). The traditional recommended ED observation time is 4–6 h …