Bedrest as an experimental paradigm or as an in-patient stay for medical reasons has
negative consequences for cardiovascular health. The effects of severe inactivity parallel …

Periods of skeletal muscle disuse lead to rapid declines in muscle mass (atrophy), which is
fundamentally underpinned by an imbalance between muscle protein synthesis (MPS) and …

Aims Active cigarette smoking is a major risk factor for chronic obstructive pulmonary
disease that remains elevated after cessation. Skeletal muscle dysfunction has been well …

Movement is life. From birth to death and every moment in between, even when we are
asleep, people move, and change position. This makes the condition of a long-term …

Skeletal muscle unloading occurs during a wide range of conditions, from space flight to bed
rest. The unloaded muscle undergoes negative functional changes, which include increased …

To critically evaluate the effects of manual therapy (MT) on pain and functional improvement
in patients with rotator cuff injury (RCI), a systematic review of all randomized controlled …

Myalgic Encephalomyelitis (ME; sometimes referred to as chronic fatigue syndrome) is a
relatively common and female-biased disease of unknown pathogenesis that profoundly …

Background The transcription factor nuclear receptor subfamily 4 group A member 3
(NR4A3) is a pleiotropic regulator of skeletal muscle metabolism. NR4A3 expression is …