Z Zhaolin, L Guohua, W Shiyuan, W Zuo - Cell proliferation, 2019 - Wiley Online Library
Cardiac function is determined by the dynamic equilibrium of various cell types and the extracellular matrix that composes the heart. Cardiovascular diseases (CVDs), especially …
H Yan, B Luo, X Wu, F Guan, X Yu, L Zhao… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Cisplatin (DDP) was reported to improve pathological complete response (pCR) rates in triple-negative breast cancer (TNBC) patients, however, the molecular mechanism still …
X Hu, Z Li, R Lin, J Shan, Q Yu, R Wang… - Frontiers in cell and …, 2021 - frontiersin.org
Over the past few years, the field of regulated cell death continues to expand and novel mechanisms that orchestrate multiple regulated cell death pathways are being unveiled …
S Zhuang, Y Ma, Y Zeng, C Lu, F Yang, N Jiang… - Cell Biology and …, 2021 - Springer
Doxorubicin (DOX) has toxic effects on the heart, causing cardiomyopathy and heart injury, but the underlying mechanisms of these effects require further investigation. This study …
ZW Yu, J Zhang, X Li, Y Wang, YH Fu, XY Gao - Life sciences, 2020 - Elsevier
Pyroptosis is a form of cell death mediated by gasdermin D (GSDMD); it is characterised by NLRP3 inflammasome activation, caspase activation, cell membrane pore formation, and …
N Ji, Z Qi, Y Wang, X Yang, Z Yan, M Li… - Journal of …, 2021 - Taylor & Francis
Pyroptosis is a kind of pro-inflammatory cell death. Compared with autophagy and apoptosis, pyroptosis has unique characteristics in morphology and mechanism …
The epidemic of diabetes mellitus (DM) necessitates the development of novel therapeutic and preventative strategies to attenuate complications of this debilitating disease. Diabetic …
XH Yu, WY Deng, JJ Chen, XD Xu, XX Liu… - Cell Death & …, 2020 - nature.com
Abstract Kcnq1 overlapping transcript 1 (kcnq1ot1), an imprinted antisense lncRNA in the kcnq1 locus, acts as a potential contributor to cardiovascular disease, but its role in …
The cellular signaling network involves co-ordinated regulation of numerous signaling molecules that aid the maintenance of cellular as well as organismal homeostasis. Aberrant …