Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging
technique that enables in vivo reconstruction of the brain's white matter connections at …

The core concept within the field of brain mapping is the use of a standardized, or
“stereotaxic”, 3D coordinate frame for data analysis and reporting of findings from …

We present VoxelMorph, a fast learning-based framework for deformable, pairwise medical
image registration. Traditional registration methods optimize an objective function for each …

Importance Cerebrospinal fluid phosphorylated tau (p-tau) 181, p-tau217, and p-tau231 are
associated with neuropathological outcomes, but a comparison of these p-tau isoforms in …

Classical deformable registration techniques achieve impressive results and offer a rigorous
theoretical treatment, but are computationally intensive since they solve an optimization …

A large range of sophisticated brain image analysis tools have been developed by the
neuroscience community, greatly advancing the field of human brain mapping. Here we …

Alzheimer's disease is increasingly considered a large-scale network disconnection
syndrome, associated with progressive aggregation of pathological proteins, cortical …

Neuropsychiatric symptoms (NPS) are very common in Alzheimer's disease (AD),
particularly agitation, apathy, depression, and delusions. Brain networks or circuits …

Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) recently added diffusion
tensor imaging (DTI), among several other new imaging modalities, in an effort to identify …

Background Total tau protein (T-Tau) and neurofilament light chain (NfL) have emerged as
candidate plasma biomarkers of neurodegeneration, but studies have not compared how …