Osteoporosis in men

T Vilaca, R Eastell, M Schini - The lancet Diabetes & endocrinology, 2022 - thelancet.com
Osteoporosis in men is a common but often overlooked disorder by clinicians. The criterion
for osteoporosis diagnosis in men is similar to that in women—namely, a bone mineral …

Basics of androgen synthesis and action

RN Elzenaty, T Du Toit, CE Flück - Best Practice & Research Clinical …, 2022 - Elsevier
Androgens are essential sex steroid hormones for both sexes. Testosterone (T) is the
predominant androgen in males, while in adult females, T concentrations are about 15-fold …

Hormonal replacement in hypopituitarism in adults: an endocrine society clinical practice guideline

M Fleseriu, IA Hashim, N Karavitaki… - The Journal of …, 2016 - academic.oup.com
Objective: To formulate clinical practice guidelines for hormonal replacement in
hypopituitarism in adults. Participants: The participants include an Endocrine Society …

Male reproductive disorders and fertility trends: influences of environment and genetic susceptibility

NE Skakkebaek, E Rajpert-De Meyts… - Physiological …, 2016 - journals.physiology.org
It is predicted that Japan and European Union will soon experience appreciable decreases
in their populations due to persistently low total fertility rates (TFR) below replacement level …

Impact of advanced paternal age on fertility and risks of genetic disorders in offspring

A Kaltsas, E Moustakli, A Zikopoulos, I Georgiou… - Genes, 2023 - mdpi.com
The average age of fathers at first pregnancy has risen significantly over the last decade
owing to various variables, including a longer life expectancy, more access to contraception …

Sex and the development of Alzheimer's disease

CJ Pike - Journal of neuroscience research, 2017 - Wiley Online Library
Men and women exhibit differences in the development and progression of Alzheimer's
disease (AD). The factors underlying the sex differences in AD are not well understood. This …

Clinical epidemiology of Alzheimer's disease: assessing sex and gender differences

MM Mielke, P Vemuri, WA Rocca - Clinical epidemiology, 2014 - Taylor & Francis
With the aging of the population, the burden of Alzheimer's disease (AD) is rapidly
expanding. More than 5 million people in the US alone are affected with AD and this number …

Gonadal steroids and body composition, strength, and sexual function in men

JS Finkelstein, H Lee, SAM Burnett-Bowie… - … England Journal of …, 2013 - Mass Medical Soc
Background Current approaches to diagnosing testosterone deficiency do not consider the
physiological consequences of various testosterone levels or whether deficiencies of …

Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring

R Sharma, A Agarwal, VK Rohra, M Assidi… - Reproductive Biology …, 2015 - Springer
Over the last decade, there has been a significant increase in average paternal age when
the first child is conceived, either due to increased life expectancy, widespread use of …

Paediatric and adult-onset male hypogonadism

A Salonia, G Rastrelli, G Hackett… - Nature reviews Disease …, 2019 - nature.com
The hypothalamic–pituitary–gonadal axis is of relevance in many processes related to the
development, maturation and ageing of the male. Through this axis, a cascade of …