Gut microbiota was only considered as a commensal organism that aids in digestion, but
recent studies revealed that the microbiome play a critical role in both physiological and …

The sequence of chromosome 21 was a turning point for the understanding of Down
syndrome. Comparative genomics is beginning to identify the functional components of the …

High-quality and complete reference genome assemblies are fundamental for the
application of genomics to biology, disease, and biodiversity conservation. However, such …

Reconstruction of target genomes from sequence data produced by instruments that are
agnostic as to the species-of-origin may be confounded by contaminant DNA. Whether …

We report genome sequences of 17 inbred strains of laboratory mice and identify almost ten
times more variants than previously known. We use these genomes to explore the …

The sequence of the mouse genome is a key informational tool for understanding the
contents of the human genome and a key experimental tool for biomedical research. Here …

Motivation: We introduce gmap, a standalone program for mapping and aligning cDNA
sequences to a genome. The program maps and aligns a single sequence with minimal …

The laboratory rat (Rattus norvegicus) is an indispensable tool in experimental medicine
and drug development, having made inestimable contributions to human health. We report …

Only a small proportion of the mouse genome is transcribed into mature messenger RNA
transcripts. There is an international collaborative effort to identify all full-length mRNA …

Presented here is a genome sequence of an individual human. It was produced from∼ 32
million random DNA fragments, sequenced by Sanger dideoxy technology and assembled …