Long non-coding RNAs regulate drug resistance in cancer

K Liu, L Gao, X Ma, JJ Huang, J Chen, L Zeng… - Molecular cancer, 2020 - Springer
Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of
cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various …

Non-coding RNAs in enzalutamide resistance of castration-resistant prostate cancer

K Gao, X Li, J Ni, B Wu, J Guo, R Zhang, G Wu - Cancer Letters, 2023 - Elsevier
Enzalutamide (Enz) is a next-generation androgen receptor (AR) antagonist used to treat
castration-resistant prostate cancer (CRPC). Unfortunately, the relapsing nature of CRPC …

Long non‐coding RNA ADAMTS9‐AS1 suppresses colorectal cancer by inhibiting the Wnt/β‐catenin signalling pathway and is a potential diagnostic biomarker

N Li, J Li, Q Mi, Y Xie, P Li, L Wang… - Journal of cellular …, 2020 - Wiley Online Library
Long non‐coding RNAs (lncRNAs) have come out as critical molecular regulators of human
tumorigenesis. In this study, we sought to identify and functionally characterize lncRNAs as …

LncRNA HOXA-AS2 promotes the progression of prostate cancer via targeting miR-509-3p/PBX3 axis

S Xiao, B Song - Bioscience reports, 2020 - portlandpress.com
Long non-coding RNAs (lncRNAs) act as crucial modulators during the development of
diverse cancers. Although various types of lncRNAs in prostate cancer (PCa) have been …

Long non-coding RNA RP11-283G6. 5 confines breast cancer development through modulating miR-188-3p/TMED3/Wnt/β-catenin signalling

J Pei, S Zhang, X Yang, C Han, Y Pan, J Li, Z Wang… - RNA biology, 2021 - Taylor & Francis
The contributions of long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) to breast
cancer are critical areas of investigation. In this study, we identified a novel lncRNA RP11 …

Roles of lncRNAs mediating Wnt/β-catenin signaling in HCC

Y Xu, X Yu, Z Sun, Y He, W Guo - Frontiers in Oncology, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is considered the second most deadly cancer worldwide.
Due to the absence of early diagnostic markers and effective therapeutic approaches …

LncFALEC recruits ART5/PARP1 and promotes castration-resistant prostate cancer through enhancing PARP1-meditated self PARylation

F Shi, L Wu, D Cui, M Sun, Y Shen, Z Zhou, Z Deng… - Cellular Oncology, 2023 - Springer
Accumulating evidence indicates that long noncoding RNAs (lncRNAs) are abnormal
expression in various malignant tumors. Our previous research demonstrated that focally …

Data-driven translational prostate cancer research: from biomarker discovery to clinical decision

Y Lin, X Zhao, Z Miao, Z Ling, X Wei, J Pu… - Journal of Translational …, 2020 - Springer
Prostate cancer (PCa) is a common malignant tumor with increasing incidence and high
heterogeneity among males worldwide. In the era of big data and artificial intelligence, the …

LNC00115 mediates Cisplatin resistance by regulating the miR-7/ERK Signalling pathway in ovarian cancer

X Jiang, Y Cheng, Y He, S Cong, L Sun… - Cancer Management …, 2021 - Taylor & Francis
Background Ovarian cancer has one of the highest mortality rates among all gynaecological
malignancies, and increasing evidence suggests that lncRNAs are widely involved in the …

[PDF][PDF] Identification of LINC01503 as Biomarker Regulated by CTBP1 with Prognostic and Diagnostic Role in Epithelial Ovarian Cancer

Y Wang, Z Wei, J Zhang, X Wang, X Li - 2021 - scholar.archive.org
Background: Epithelial ovarian cancer (EOC) is a disease with high morbidity and mortality
worldwide, which is seriously harmful to female health. LncRNA has an important …