Zinc and human health: an update

CT Chasapis, AC Loutsidou, CA Spiliopoulou… - Archives of …, 2012 - Springer
The importance of micronutrients in health and nutrition is undisputable, and among them,
zinc is an essential element whose significance to health is increasingly appreciated and …

Zinc: a multipurpose trace element

M Stefanidou, C Maravelias, A Dona… - Archives of toxicology, 2006 - Springer
Zinc (Zn) is one of the most important trace elements in the body and it is essential as a
catalytic, structural and regulatory ion. It is involved in homeostasis, in immune responses, in …

Insights into thymic aging and regeneration

DD Taub, DL Longo - Immunological reviews, 2005 - Wiley Online Library
The deterioration of the immune system with progressive aging is believed to contribute to
morbidity and mortality in elderly humans due to the increased incidence of infection …

[图书][B] Нейроиммуноэндокринология тимуса

ИА Кветной, АА Ярилин, ВО Полякова, ИВ Князькин - 2005 - elibrary.ru
Монография посвящена нейроиммуноэндокринологии тимуса. Описаны внутри-и
межклеточные молекулярные процессы сигнальной регуляции пролиферации …

The role of sex steroids and gonadectomy in the control of thymic involution

M Hince, S Sakkal, K Vlahos, J Dudakov, R Boyd… - Cellular …, 2008 - Elsevier
A major underlying cause for aging of the immune system is the structural and functional
atrophy of the thymus, and associated decline in T cell genesis. This loss of naïve T cells …

The role of immunity in elderly cancer

L Malaguarnera, E Cristaldi, M Malaguarnera - Critical reviews in oncology …, 2010 - Elsevier
The increased incidence of malignancies in elderly patients living in industrialized countries
has led to both identify the causes that alter the normal homeostatic balance in elderly and …

[HTML][HTML] Therapeutic application of zinc in human immunodeficiency virus against opportunistic infections

E Mocchegiani, M Muzzioli - The Journal of nutrition, 2000 - Elsevier
The relevance of zinc in resistance to infections by virus, fungi and bacteria is recognized
because of its pivotal role in the efficiency of the entire immune system, in particular in …

Zinc, metallothioneins, immune responses, survival andageing

E Mocchegiani, M Muzzioli, R Giacconi - Biogerontology, 2000 - Springer
Zinc is required as a catalytic, structural (zincfingers) and regulatory ion. In this capacity, it
isinvolved in many homeostatic mechanisms, includingimmune responses. Metallothioneins …

Metallothioneins/PARP-1/IL-6 interplay on natural killer cell activity in elderly: parallelism with nonagenarians and old infected humans. Effect of zinc supply

E Mocchegiani, M Muzzioli, R Giacconi… - Mechanisms of ageing …, 2003 - Elsevier
Metallothioneins (MTs) play pivotal role in zinc-related cell homeostasis because of their
high affinity for this trace element which is in turn relevant against oxidative stress and for the …

MacrophAging: a cellular and molecular review

C Sebastián, M Espia, M Serra, A Celada, J Lloberas - Immunobiology, 2005 - Elsevier
Aging is associated with the deterioration of several physiological functions, which leads to
aged-related pathologies and, ultimately, to death. The immune system is affected by aging …