Decades of research advances have established a central role for endogenous opioid
systems in regulating reward processing, mood, motivation, learning and memory …

Background: Traditional pain assessment methods have significant limitations due to the
high variability in patient reported pain scores and perception of pain by different individuals …

Background Chronic pain affects about 20% of the Canadian population and can lead to
physical, psychological and social vulnerabilities. However, this condition remains poorly …

Background: Spinal cord stimulation has been utilized with increasing frequency in
managing chronic intractable spinal pain and complex regional pain syndrome (CRPS) in …

Fentanyl is a potent narcotic drug with the same effects as morphine or heroin, but it's
significantly more potent than these drugs. That means a tiny dose can have a dangerous …

Background: Regenerative medicine interventions are applied to assist in the repair, and to
potentially replace or restore damaged tissue through the use of autologous/allogenic …

Introduction The COVID-19 pandemic has had a variable effect on vulnerable populations,
including patients with chronic pain who rely on opioid treatment or have comorbid opioid …

Global health governance is a developing system in this complex institutional regime. The
local and regional health policies sometimes challenge global health governance due to …

Since the early 2010s, synthetic opioids have significantly contributed to overall opioid-
related overdose mortalities. For point of reference, of the 68,630 opioid-related deaths …

Introduction The COVID-19 pandemic resulted in major disruptions in all aspects of human
life including a decline of medical services utilized during 2020. An analysis of the impact of …