[HTML][HTML] Diet-induced models of non-alcoholic fatty liver disease: food for thought on sugar, fat, and cholesterol

JM Eng, JL Estall - Cells, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) affects approximately 1 in 4 people worldwide and
is a major burden to health care systems. A major concern in NAFLD research is lack of …

Current innovations in nutraceuticals and functional foods for intervention of non-alcoholic fatty liver disease

M Zhao, S Chen, X Ji, X Shen, J You, X Liang… - Pharmacological …, 2021 - Elsevier
As innovations in global agricultural production and food trading systems lead to major
dietary shifts, high morbidity rates from non-alcoholic fatty liver disease (NAFLD) …

[HTML][HTML] Melatonin effects on non-alcoholic fatty liver disease are related to microRNA-34a-5p/Sirt1 axis and autophagy

A Stacchiotti, I Grossi, R García-Gómez, GA Patel… - Cells, 2019 - mdpi.com
Melatonin, an indole produced by pineal and extrapineal tissues, but also taken with a
vegetarian diet, has strong anti-oxidant, anti-inflammatory and anti-obesogenic potentials …

Different effects of high-fat diets rich in different oils on lipids metabolism, oxidative stress and gut microbiota

H Liu, H Zhu, H Xia, X Yang, L Yang, S Wang… - Food Research …, 2021 - Elsevier
The study aimed to investigate the different effects of high-fat (HF) diets rich in different oils
on lipid metabolism, oxidative stress, and gut mirobiota. C57BL/6 mice were divided into 4 …

[HTML][HTML] Sulfur dioxide-free wine with polyphenols promotes lipid metabolism via the Nrf2 pathway and gut microbiota modulation

Y Ma, K Yu, N Wang, X Xiao, Y Leng, J Fan, Y Du… - Food Chemistry: X, 2024 - Elsevier
Moderate wine consumption is often associated with preventing obesity, yet concerns arise
due to the health risks linked to its constituent antioxidant, SO 2. Recent focus has turned to …

[HTML][HTML] Tempol protects against acetaminophen induced acute hepatotoxicity by inhibiting oxidative stress and apoptosis

Z Ge, C Wang, J Zhang, X Li, J Hu - Frontiers in Physiology, 2019 - frontiersin.org
Acetaminophen (APAP)-induced acute hepatotoxicity is the leading cause of drug-induced
acute liver failure. The aim of this study was to evaluate the effects of 4-hydroxy-2, 2, 6, 6 …

[HTML][HTML] High-fat diet enhances starvation-induced hyperactivity via sensitizing hunger-sensing neurons in Drosophila

R Huang, T Song, H Su, Z Lai, W Qin, Y Tian, X Dong… - Elife, 2020 - elifesciences.org
The function of the central nervous system to regulate food intake can be disrupted by
sustained metabolic challenges such as high-fat diet (HFD), which may contribute to various …

[HTML][HTML] Reduced oxidative stress and enhanced FGF21 formation in livers of endurance-exercised rats with diet-induced NASH

J Henkel, K Buchheim-Dieckow, JP Castro, T Laeger… - Nutrients, 2019 - mdpi.com
Non-alcoholic fatty liver diseases (NAFLD) including the severe form with steatohepatitis
(NASH) are highly prevalent ailments to which no approved pharmacological treatment …

[HTML][HTML] Attenuating effect of Polygala tenuifolia Willd. seed oil on progression of MAFLD

M Xin, H Wang, M Wang, B Yang, S Liang… - Frontiers in …, 2023 - frontiersin.org
Introduction: Metabolic-associated fatty liver disease (MAFLD) is a common chronic
metabolic disease that seriously threatens human health. The pharmacological activity of …

Deciphering the molecular pathways of saroglitazar: A dual PPAR α/γ agonist for managing metabolic NAFLD

D Ezhilarasan - Metabolism, 2024 - Elsevier
Saroglitazar (SARO), a dual peroxisome proliferator activated receptor (PPAR)-α/γ agonist,
has been used to treat metabolic diseases such as insulin resistance and diabetic …