Tumor Cells-derived exosomal CircRNAs: Novel cancer drivers, molecular mechanisms, and clinical opportunities

A Vahabi, J Rezaie, M Hassanpour, Y Panahi… - Biochemical …, 2022 - Elsevier
Recently, circular RNAs (circRNAs) have appealed to a growing interest due to their
abundant expression and potential functions in cancer development. The most biological …

Application of stem cell-derived exosomes in ischemic diseases: opportunity and limitations

M Babaei, J Rezaie - Journal of translational medicine, 2021 - Springer
Ischemic diseases characterized by an insufficient blood flow that leads to a decrease in
oxygen and nutrient uptake by cells have emerged as an important contributor to both …

The distinct roles of exosomes in innate immune responses and therapeutic applications in cancer

J Rezaie, T Etemadi, M Feghhi - European journal of pharmacology, 2022 - Elsevier
The innate immune system is one of the major constituents of the host's defense against
invading pathogens and extracellular vesicles (EVs) are involved in regulating its …

Potential therapeutic application of mesenchymal stem cell-derived exosomes in SARS-CoV-2 pneumonia

A Akbari, J Rezaie - Stem cell research & therapy, 2020 - Springer
Background The outbreak of a new virus known as severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has now become the main health concern all over the world …

Hypoxic exosomes orchestrate tumorigenesis: molecular mechanisms and therapeutic implications

R Jafari, R Rahbarghazi, M Ahmadi… - Journal of Translational …, 2020 - Springer
The solid tumor microenvironment possesses a hypoxic condition, which promotes
aggressiveness and resistance to therapies. Hypoxic tumor cells undergo broadly metabolic …

Ageing and mesenchymal stem cells derived exosomes: molecular insight and challenges

M Ahmadi, J Rezaie - Cell Biochemistry and Function, 2021 - Wiley Online Library
Ageing induces a great risk factor that participates in progressing various degenerative
diseases morbidities. The main characteristic of ageing is the failure in maintaining …

[HTML][HTML] Silver nanoparticles induce the cardiomyogenic differentiation of bone marrow derived mesenchymal stem cells via telomere length extension

K Adibkia, A Ehsani, A Jodaei, E Fathi… - Beilstein journal of …, 2021 - beilstein-journals.org
Finding new strategies for the treatment of heart failures using stem cells has attracted a lot
of attention. Meanwhile, nanotechnology-based approaches to regenerative medicine …

[HTML][HTML] Effect of multi-functional polyhydroxylated polyhedral oligomeric silsesquioxane (POSS) nanoparticles on the angiogenesis and exosome biogenesis in …

M Feghhi, J Rezaie, A Akbari, N Jabbari, H Jafari… - Materials & Design, 2021 - Elsevier
Angiogenesis, the growth of new vessels, is a vital process for tissue regeneration.
Exosomes are nano-sized vesicles releasing from cells that are recognized as important …

Distinct role of autophagy on angiogenesis: highlights on the effect of autophagy in endothelial lineage and progenitor cells

M Hassanpour, A Rezabakhsh, M Pezeshkian… - Stem cell research & …, 2018 - Springer
Autophagy plays a critical role in the dynamic growth of each cell through different
conditions. It seems that this intracellular mechanism acts as a two-edged sword against the …

Ischemia induces autophagy of endothelial cells and stimulates angiogenic effects in a hindlimb ischemia mouse model

IH Jeong, WY Bae, JS Choi, JW Jeong - Cell death & disease, 2020 - nature.com
Although peripheral artery disease (PAD) is a major health problem, there have been limited
advances in medical therapies. In PAD patients, angiogenesis is regarded as a promising …