[HTML][HTML] Building digital twins of the human immune system: toward a roadmap
Digital twins, customized simulation models pioneered in industry, are beginning to be
deployed in medicine and healthcare, with some major successes, for instance in …
deployed in medicine and healthcare, with some major successes, for instance in …
The reactome pathway knowledgebase 2022
Abstract The Reactome Knowledgebase (https://reactome. org), an Elixir core resource,
provides manually curated molecular details across a broad range of physiological and …
provides manually curated molecular details across a broad range of physiological and …
[HTML][HTML] Immune landscape and redox imbalance during neurological disorders in COVID-19
Abstract The outbreak of Coronavirus Disease 2019 (COVID-19) has prompted the scientific
community to explore potential treatments or vaccines against severe acute respiratory …
community to explore potential treatments or vaccines against severe acute respiratory …
WikiPathways 2024: next generation pathway database
WikiPathways (wikipathways. org) is an open-source biological pathway database.
Collaboration and open science are pivotal to the success of WikiPathways. Here we …
Collaboration and open science are pivotal to the success of WikiPathways. Here we …
Integrated intra‐and intercellular signaling knowledge for multicellular omics analysis
D Türei, A Valdeolivas, L Gul… - Molecular systems …, 2021 - embopress.org
Molecular knowledge of biological processes is a cornerstone in omics data analysis.
Applied to single‐cell data, such analyses provide mechanistic insights into individual cells …
Applied to single‐cell data, such analyses provide mechanistic insights into individual cells …
[HTML][HTML] A proteome-scale map of the SARS-CoV-2–human contactome
Understanding the mechanisms of coronavirus disease 2019 (COVID-19) disease severity
to efficiently design therapies for emerging virus variants remains an urgent challenge of the …
to efficiently design therapies for emerging virus variants remains an urgent challenge of the …
Automated assembly of molecular mechanisms at scale from text mining and curated databases
The analysis of omic data depends on machine‐readable information about protein
interactions, modifications, and activities as found in protein interaction networks, databases …
interactions, modifications, and activities as found in protein interaction networks, databases …
[HTML][HTML] Building a FAIR image data ecosystem for microscopy communities
I Kemmer, A Keppler, B Serrano-Solano… - Histochemistry and Cell …, 2023 - Springer
Bioimaging has now entered the era of big data with faster-than-ever development of
complex microscopy technologies leading to increasingly complex datasets. This enormous …
complex microscopy technologies leading to increasingly complex datasets. This enormous …
[HTML][HTML] Semantic interoperability: ontological unpacking of a viral conceptual model
Background Genomics and virology are unquestionably important, but complex, domains
being investigated by a large number of scientists. The need to facilitate and support work …
being investigated by a large number of scientists. The need to facilitate and support work …
Addressing barriers in comprehensiveness, accessibility, reusability, interoperability and reproducibility of computational models in systems biology
Computational models are often employed in systems biology to study the dynamic
behaviours of complex systems. With the rise in the number of computational models, finding …
behaviours of complex systems. With the rise in the number of computational models, finding …