Pathophysiology and mechanism of long COVID: a comprehensive review

D Castanares-Zapatero, P Chalon, L Kohn… - Annals of …, 2022 - Taylor & Francis
Background After almost 2 years of fighting against SARS-CoV-2 pandemic, the number of
patients enduring persistent symptoms long after acute infection is a matter of concern. This …

[HTML][HTML] Long COVID and its Management

HC Koc, J Xiao, W Liu, Y Li, G Chen - International journal of …, 2022 - ncbi.nlm.nih.gov
The pandemic of COVID-19 is the biggest public health crisis in 21 st Century. Besides the
acute symptoms after infection, patients and society are also being challenged by the long …

[HTML][HTML] Long COVID endotheliopathy: hypothesized mechanisms and potential therapeutic approaches

J Ahamed, J Laurence - The Journal of clinical investigation, 2022 - Am Soc Clin Investig
SARS-CoV-2–infected individuals may suffer a multi–organ system disorder known as “long
COVID” or post-acute sequelae of SARS-CoV-2 infection (PASC). There are no standard …

Epidemiology, clinical presentation, pathophysiology, and management of long COVID: an update

S Su, Y Zhao, N Zeng, X Liu, Y Zheng, J Sun… - Molecular …, 2023 - nature.com
The increasing number of coronavirus disease 2019 (COVID-19) infections have highlighted
the long-term consequences of severe acute respiratory syndrome coronavirus 2 (SARS …

[HTML][HTML] Post-COVID syndrome: an insight on its pathogenesis

HC Maltezou, A Pavli, A Tsakris - Vaccines, 2021 - mdpi.com
Post-COVID syndrome is increasingly recognized as a new clinical entity in the context of
SARS-CoV-2 infection. Symptoms persisting for more than three weeks after the diagnosis of …

Persistent neuropsychiatric symptoms after COVID-19: a systematic review and meta-analysis

JB Badenoch, ER Rengasamy, C Watson… - Brain …, 2022 - academic.oup.com
The nature and extent of persistent neuropsychiatric symptoms after COVID-19 are not
established. To help inform mental health service planning in the pandemic recovery phase …

[HTML][HTML] Biomarkers in long COVID-19: A systematic review

YJ Lai, SH Liu, S Manachevakul, TA Lee… - Frontiers in …, 2023 - frontiersin.org
Purpose Long COVID, also known as post-acute sequelae of COVID-19, refers to the
constellation of long-term symptoms experienced by people suffering persistent symptoms …

[HTML][HTML] Long COVID-19 syndrome: a comprehensive review of its effect on various organ systems and recommendation on rehabilitation plans

Z Yan, M Yang, CL Lai - Biomedicines, 2021 - mdpi.com
The majority of people infected with SARS-CoV-2 fully recovered within a few weeks.
However, a considerable number of patients of different ages still suffer from long-lasting …

[HTML][HTML] SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice

FL Fontes-Dantas, GG Fernandes, EG Gutman… - Cell reports, 2023 - cell.com
Cognitive dysfunction is often reported in patients with post-coronavirus disease 2019
(COVID-19) syndrome, but its underlying mechanisms are not completely understood …

SARS‐CoV‐2 and mitochondrial proteins in neural‐derived exosomes of COVID‐19

MJ Peluso, SG Deeks, M Mustapic… - Annals of …, 2022 - Wiley Online Library
Objective As SARS‐CoV‐2 is known to invade neural cell mitochondria, a plasma system for
quantifying central nervous system proteins in living humans was used to investigate …