Several different reactive oxygen species (ROS) are generated in vivo. They have roles in
the development of certain human diseases whilst also performing physiological functions …

Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …

Background Biological ageing is tightly linked to cardiovascular disease (CVD). We aimed to
investigate the relationship between Life's Essential 8 (LE8), a currently updated measure of …

Exercise training prevents age‐related decline in muscle function. Targeting epigenetic
aging is a promising actionable mechanism and late‐life exercise mitigates epigenetic aging …

Physical activity, including walking, has numerous health benefits in older adults, supported
by a plethora of observational and interventional studies. Walking decreases the risk or …

Ageing is a complex biological process associated with increased morbidity and mortality.
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …

Chronic low-grade elevations of blood-borne cytokines/chemokines in older age tend to
associate with frailty in humans. This persistent inflammation is often called “inflammageing” …

Vascular aging, featuring endothelial dysfunction and large elastic artery stiffening, is a
major risk factor for the development of age-associated cardiovascular diseases (CVDs) …

Introduction The incidence of rheumatoid arthritis (RA) and its complications are expected to
increase with age. Remarkably, RA patients were identified features of accelerated aging …

As an organism ages, its health-state is determined by a balance between the processes of
damage and repair. Measuring these processes requires longitudinal data. We extract …