T cell receptor‐based cancer immunotherapy: emerging efficacy and pathways of resistance

SS Chandran, CA Klebanoff - Immunological reviews, 2019 - Wiley Online Library
Adoptive cell transfer (ACT) using chimeric antigen receptor (CAR)‐modified T cells can
induce durable remissions in patients with refractory B‐lymphoid cancers. By contrast …

Modifications and functional genomics of human transfer RNA

T Pan - Cell research, 2018 - nature.com
Transfer RNA (tRNA) is present at tens of millions of transcripts in a human cell and is the
most abundant RNA in moles among all cellular RNAs. tRNA is also the most extensively …

The ipd-imgt/hla database

DJ Barker, G Maccari, X Georgiou… - Nucleic acids …, 2023 - academic.oup.com
It is 24 years since the IPD-IMGT/HLA Database, http://www. ebi. ac. uk/ipd/imgt/hla/, was
first released, providing the HLA community with a searchable repository of highly curated …

Ipd-imgt/hla database

J Robinson, DJ Barker, X Georgiou… - Nucleic acids …, 2020 - academic.oup.com
Abstract The IPD-IMGT/HLA Database, http://www. ebi. ac. uk/ipd/imgt/hla/, currently
contains over 25 000 allele sequence for 45 genes, which are located within the Major …

HLA allele frequencies and susceptibility to COVID‐19 in a group of 99 Italian patients

A Novelli, M Andreani, M Biancolella, L Liberatoscioli… - Hla, 2020 - Wiley Online Library
With the aim to individuate alleles that may reflect a higher susceptibility to the disease, in
the present study we analyzed the HLA allele frequency distribution in a group of 99 Italian …

The IPD and IMGT/HLA database: allele variant databases

J Robinson, JA Halliwell, JD Hayhurst… - Nucleic acids …, 2015 - academic.oup.com
Abstract The Immuno Polymorphism Database (IPD) was developed to provide a centralized
system for the study of polymorphism in genes of the immune system. Through the IPD …

[HTML][HTML] Gender differences in autoimmune disease

ST Ngo, FJ Steyn, PA McCombe - Frontiers in neuroendocrinology, 2014 - Elsevier
Autoimmune diseases are a range of diseases in which the immune response to self-
antigens results in damage or dysfunction of tissues. Autoimmune diseases can be systemic …

Efficient and quantitative high-throughput tRNA sequencing

G Zheng, Y Qin, WC Clark, Q Dai, C Yi, C He… - Nature …, 2015 - nature.com
Despite its biological importance, tRNA has not been adequately sequenced by standard
methods because of its abundant post-transcriptional modifications and stable structure …

Adaptive and innate immunity in psoriasis and other inflammatory disorders

MP Schön - Frontiers in immunology, 2019 - frontiersin.org
Over the past three decades, a considerable body of evidence has highlighted T cells as
pivotal culprits in the pathogenesis of psoriasis. This includes the association of psoriasis …

HLA, immune response, and susceptibility to COVID-19

F Tavasolian, M Rashidi, GR Hatam, M Jeddi… - Frontiers in …, 2021 - frontiersin.org
The severe acute respiratory syndrome caused by Coronavirus 2 (SARS-CoV-2) that
appeared in December 2019 has precipitated the global pandemic Coronavirus Disease …