MicroRNAs in molecular classification and pathogenesis of breast tumors

V Richard, MG Davey, H Annuk, N Miller, RM Dwyer… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is an ideal model of a heterogeneous disease that is
triggered by genetic changes in the normal mammary epithelial cells and manifest as …

A review of ULK1-mediated autophagy in drug resistance of cancer

L Liu, L Yan, N Liao, WQ Wu, JL Shi - Cancers, 2020 - mdpi.com
The difficulty of early diagnosis and the development of drug resistance are two major
barriers to the successful treatment of cancer. Autophagy plays a crucial role in several …

[HTML][HTML] Glyphosate primes mammary cells for tumorigenesis by reprogramming the epigenome in a TET3-dependent manner

M Duforestel, A Nadaradjane, G Bougras-Cartron… - Frontiers in …, 2019 - frontiersin.org
The acknowledgment that pollutants might influence the epigenome raises serious concerns
regarding their long-term impact on the development of chronic diseases. The herbicide …

LINC00680 and TTN-AS1 stabilized by EIF4A3 promoted malignant biological behaviors of glioblastoma cells

W Tang, D Wang, L Shao, X Liu, J Zheng, Y Xue… - … Therapy-Nucleic Acids, 2020 - cell.com
Glioblastomas are the most common and malignant intracranial tumors with a low survival
rate. Dysregulation of long non-coding RNAs and RNA-binding protein causes various …

LncRNA SNHG1 contributes to the regulation of acute myeloid leukemia cell growth by modulating miR‐489‐3p/SOX12/Wnt/β‐catenin signaling

C Li, Q Gao, M Wang, H Xin - Journal of Cellular Physiology, 2021 - Wiley Online Library
The long noncoding RNA (lncRNA) small nucleolar RNA host gene 1 (SNHG1) is a critical
regulator for the development and progression of multiple tumors. Yet, the role of SNHG1 in …

MicroRNAs: a link between mammary gland development and breast cancer

D Wu, LU Thompson, EM Comelli - International Journal of Molecular …, 2022 - mdpi.com
Breast cancer is among the most common cancers in women, second to skin cancer.
Mammary gland development can influence breast cancer development in later life …

MicroRNA-489-3p attenuates neuropathic allodynia by regulating oncoprotein DEK/TET1-dependent epigenetic modification in the dorsal horn

CY Lai, MC Hsieh, CM Yeh, PS Yang, JK Cheng… - …, 2022 - Elsevier
Originally characterized as an oncoprotein overexpressed in many forms of cancer that
participates in numerous cellular pathways, DEK has since been well described regarding …

Hepsin regulates TGFβ signaling via fibronectin proteolysis

D Belitškin, SM Pant, P Munne, I Suleymanova… - EMBO …, 2021 - embopress.org
Transforming growth factor‐beta (TGFβ) is a multifunctional cytokine with a well‐established
role in mammary gland development and both oncogenic and tumor‐suppressive functions …

MicroRNAs and Stem-like Properties: The complex regulation underlying stemness maintenance and cancer development

G Divisato, S Piscitelli, M Elia, E Cascone, S Parisi - Biomolecules, 2021 - mdpi.com
Embryonic stem cells (ESCs) have the extraordinary properties to indefinitely proliferate and
self-renew in culture to produce different cell progeny through differentiation. This latter …

MiR-489 inhibited the development of gastric cancer via regulating HDAC7 and PI3K/AKT pathway

H Zhang, L Li, C Yuan, C Wang, T Gao… - World journal of surgical …, 2020 - Springer
Background Mounting evidences have displayed that the dysregulation of miRNAs plays
important roles in the pathogenesis of gastric cancer (GC). The purpose of this study was to …