We provide an overview on the use of biological assays to calibrate and initialize
mechanism-based models of cancer phenomena. Although artificial intelligence methods …

Flaxseed has been recognized as a valuable source of nutrients and bioactive compounds,
including proteins that possess various health benefits. In recent years, studies have shown …

Metastasis is the main cause of cancer-related mortality; therefore, the ability to predict its
propensity can remarkably affect survival rate. Metastasis development is predicted …

Cancer stem-like cells (CSCs) are a typically small subpopulation of highly tumorigenic cells
that can self-renew, differentiate, drive tumor progression, and may mediate drug resistance …

We demonstrate the relative roles of the cell cytoskeleton, and specific importance of actin in
facilitating mechanical aspects of metastatic invasion. A crucial step in metastasis, the …

Metastases are the leading cause of cancer‐associated deaths. A key process in metastasis
is cell invasiveness, which is driven and controlled by cancer cell interactions with their …

We show that cell-applied, normal mechanical stresses are required for cells to penetrate
into soft substrates, matching experimental observations in invasive cancer cells, while in …

Solid-tumor cell invasion typically occurs by collective migration of attached cell-cohorts, yet
we show here that indirect cell-interactions through the substrate can also drive …

The major cause (more than 90%) of all cancer-related deaths is metastasis, thus its
prediction can critically affect the survival rate. Metastases are currently predicted by lymph …

Cancer cell migration between different body parts is the driving force behind cancer
metastasis, which is the main cause of mortality of patients. Migration of cancer cells often …