Use of computational fluid dynamics deposition modeling in respiratory drug delivery

PW Longest, K Bass, R Dutta, V Rani… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Respiratory drug delivery is a surprisingly complex process with a number of
physical and biological challenges. Computational fluid dynamics (CFD) is a scientific …

Development of human respiratory airway models: A review

K Ahookhosh, O Pourmehran, H Aminfar… - European Journal of …, 2020 - Elsevier
Pulmonary drug delivery has gained great interest as an important subject of research over
the past decades given the lung diseases which are affecting millions of people suffer from …

Study on the coal dust deposition fraction and site in the upper respiratory tract under different particle sizes and labor intensities

Y Cheng, H Yu, S Xie, J Zhao, Y Ye - Science of The Total Environment, 2023 - Elsevier
In order to study the dust exposure amount and coal dust deposition rule of coal miners
under different labor intensity in coal mine environment, an airflow-particle two-phase …

Health effects of particulate matter in major Indian cities

N Manojkumar, B Srimuruganandam - International journal of …, 2021 - Taylor & Francis
Background: Particulate matter (PM) is one among the crucial air pollutants and has the
potential to cause a wide range of health effects. Indian cities ranked top places in the World …

[HTML][HTML] In vitro evaluation of nasal aerosol depositions: an insight for direct nose to brain drug delivery

A Maaz, IS Blagbrough, PA De Bank - Pharmaceutics, 2021 - mdpi.com
The nasal cavity is an attractive route for both local and systemic drug delivery and holds
great potential for access to the brain via the olfactory region, an area where the blood–brain …

Study on the transport and deposition of micron-sized particles with different densities in the coal mine environment in miners

Y Cheng, H Yu, Y Ye, Y Xie, J Zhao, S Xie - Fuel, 2024 - Elsevier
To address the health problems caused by the long-term intrusion of high-concentration dust
generated in coal mining operations into the human respiratory tract, this study …

In vitro–in vivo correlation of intranasal drug deposition

S Le Guellec, S Ehrmann, L Vecellio - Advanced Drug Delivery Reviews, 2021 - Elsevier
In vitro–in vivo correlation (IVIVC) allows prediction of in vivo drug deposition from a nasally
inhaled drug based on in vitro drug measurements. In vitro measurements include physical …

In Vivo–In Vitro Correlations: Predicting Pulmonary Drug Deposition from Pharmaceutical Aerosols

PR Byron, M Hindle, CF Lange… - Journal of aerosol …, 2010 - liebertpub.com
In order to answer the question “what research remains to be done?” we review the current
state of the art in pharmaceutical aerosol deposition modeling and explore possible in vivo …

[HTML][HTML] Polydisperse aerosol transport and deposition in upper airways of age-specific lung

MS Islam, P Larpruenrudee, SI Hossain… - International journal of …, 2021 - mdpi.com
A comprehensive understanding of airflow characteristics and particle transport in the
human lung can be useful in modelling to inform clinical diagnosis, treatment, and …

Simulation of airflow and aerosol deposition in the nasal cavity of a 5-year-old child

J Xi, X Si, JW Kim, A Berlinski - Journal of Aerosol Science, 2011 - Elsevier
As a human grows from birth to adulthood, both airway anatomy and breathing conditions
vary that alter the deposition rate and pattern of inhaled aerosols. However, deposition …