Many cognitive abilities decline with age even in the absence of detectable pathology.
Recent evidence indicates that age-related neural dedifferentiation, operationalized in terms …

Age-related cognitive changes often include difficulties in retrieving memories, particularly
those that rely on personal experiences within their temporal and spatial contexts (ie …

Elevated prefrontal cortex activity is often observed in healthy older adults despite declines
in their memory and other cognitive functions. According to one view, this activity reflects a …

Normal aging is associated with cognitive decline and underlying brain dysfunction.
Previous studies concentrated less on brain network changes at a systems level. Our goal …

Semantic cognition is central to understanding of language and the world and, unlike many
cognitive domains, is thought to show little age-related decline. We investigated age-related …

Background and Objectives We assessed whether novelty-related fMRI activity in medial
temporal lobe regions and the precuneus follows an inverted U-shaped pattern across the …

According to prominent theories of aging, the brain may reorganize to compensate for neural
deterioration and prevent or offset cognitive decline. A frequent and striking finding in …

Functional magnetic resonance imaging (fMRI) was used to investigate whether age-related
differences in episodic memory performance are accompanied by a reduction in the …

Mind wandering, defined as focusing attention towards task-unrelated thoughts, is a
common mental state known to impair memory encoding. This phenomenon is closely linked …

The development of the brain, particularly the protracted maturation of the prefrontal cortex
(PFC), supports the development of episodic memory. Yet how different regions of the PFC …