Lung cancer remains the leading cause of cancer-related deaths globally, and the survival
rate remains low despite advances in diagnosis and treatment. The progression of lung …

While the field of precision oncology is rapidly expanding and more targeted options are
revolutionizing cancer treatment paradigms, therapeutic resistance particularly to …

Aim: Exosomal damage-associated molecular patterns can play a key role in
immunostimulation and changing the cold tumor microenvironment to hot. Materials & …

Because therapeutic cancer vaccines can, in theory, eliminate tumor cells specifically with
relatively low toxicity, they have long been considered for application in repressing cancer …

Immune checkpoint inhibitor (ICI) therapy has revolutionized the treatment of cancer, in
particular lung cancer, while the introduction of predictive biomarkers from liquid biopsies …

Chimeric antigen receptor T-cell (CAR-T) therapy is a novel anticancer therapy using
autologous or allogeneic T-cells. To date, six CAR-T therapies for specific B-cell acute …

Exosomes are increasingly recognized as important mediators of intercellular
communication in cancer biology. Exosomes can be derived from cancer cells as well as …

Glucocorticoids (GCs), a class of hormones secreted by the adrenal glands, are released
into the bloodstream to maintain homeostasis and modulate responses to various stressors …

Methods A systematic search was conducted in PubMed and Web of Science to identify
articles investigating clinical significance and mechanisms of SCSMs. Study eligibility was …

Human umbilical vein endothelial cells (HUVECs) are primary cells isolated from the vein of
an umbilical cord, extensively used in cardiovascular studies and medical research. These …