[HTML][HTML] Nutraceutical-based telomerase inhibitors: Renewed hope for cancer therapy

YF Mustafa - Phytomedicine Plus, 2024 - Elsevier
Background: Attributes of potential targets for anticancer therapy are currently being
investigated for telomeres, telomerase, and their combined complex. Study Design …

Eu3+-Functionalized Covalent Organic Framework Hybrid Material as a Sensitive Turn-On Fluorescent Switch for Levofloxacin Monitoring in Serum and Urine

JM Wang, X Lian, B Yan - Inorganic Chemistry, 2019 - ACS Publications
The research on luminescent lanthanide-functionalized covalent organic framework (COF)-
based hybrid materials has not been reported so far. When a straightforward functionalized …

A review on sensing mechanisms and strategies for telomerase activity detection

D Wang, W Xue, X Ren, Z Xu - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
Telomerase is a valuable biomarker for early diagnosis and prognosis of cancer, as well as
anticancer-drug screening. In this review, we focus on the general sensing mechanisms …

Dual biomineralized metal− organic frameworks-mediated conversion of chemical energy to electricity enabling portable PEC sensing of telomerase activity in bladder …

F Li, M Xu, J Zhuang - Biosensors and Bioelectronics, 2022 - Elsevier
In this work, we report on a portable photoelectrochemical (PEC) sensing system for
telomerase activity detection based on dual biomineralized ZIF-8 nanoparticles (NPs) …

Electrocatalysis of cerium metal-organic frameworks for ratiometric electrochemical detection of telomerase activity

P Dong, L Zhu, J Huang, J Ren, J Lei - Biosensors and Bioelectronics, 2019 - Elsevier
A ratiometric electrochemical biosensor was constructed to detect telomerase activity based
on electrocatalysis of cerium-based metal-organic frameworks (CeMOFs) and conformation …

Improving covalent organic frameworks fluorescence by triethylamine pinpoint surgery as selective biomarker sensor for diabetes mellitus diagnosis

J Wang, B Yan - Analytical chemistry, 2019 - ACS Publications
The nitrogen-containing imine or hydrazone linked covalent organic frameworks (COFs) are
poorly luminescent due to the fluorescence quenching by nitrogen atoms in the linkages …

Construction of a Dendritic Nanoassembly-Based Fluorescent Biosensor for Electrostatic Interaction-Independent and Label-Free Measurement of Human Poly (ADP …

S Jiang, J Ren, Q Zhang, W Liu, H Liu, Q Xu… - Analytical …, 2023 - ACS Publications
Poly (ADP-ribose) polymerase 1 (PARP-1) is responsible for catalyzing the creation of poly
(ADP-ribose) polymer and involved in DNA replication and repair. Sensitive measurement of …

Tetrahedron Probes for Ultrasensitive In Situ Detection of Telomerase and Surface Glycoprotein Activity in Living Cells

X Guo, X Wu, M Sun, L Xu, H Kuang, C Xu - Analytical chemistry, 2019 - ACS Publications
In the present study, a tetrahedron probe with encoded internal reference nanoparticles
(NPs) was self-assembled by a complementary nucleic acid aptamer for simultaneous …

Plasmonic colorimetric biosensor for visual detection of telomerase activity based on horseradish peroxidase-encapsulated liposomes and etching of Au …

D Wang, Y Zhang, X Zhao, Z Xu - Sensors and Actuators B: Chemical, 2019 - Elsevier
Telomerase aberrant activation is a critical feature in the vast majority of cancers. To
visualize telomerase expression level in tumor cells, we developed a plasmonic colorimetric …

Quartz crystal microbalance detection of poly (ADP-ribose) polymerase-1 based on gold nanorods signal amplification

H Yang, P Li, D Wang, Y Liu, W Wei, Y Zhang… - Analytical …, 2019 - ACS Publications
Recent findings have thrust poly (ADP-ribose) polymerase-1 (PARP-1) into the limelight as a
potential biomarker and chemotherapeutic target for cancer. Thus, a sensitive method for …