[HTML][HTML] Revisiting the role of CD4+ T cells in cancer immunotherapy—new insights into old paradigms
Cancer immunotherapy has revolutionised cancer treatment, with immune checkpoint
blockade (ICB) therapy and adoptive cell therapy (ACT) increasingly becoming standard of …
blockade (ICB) therapy and adoptive cell therapy (ACT) increasingly becoming standard of …
CD4+ T cell help in cancer immunology and immunotherapy
Cancer immunotherapy aims to promote the activity of cytotoxic T lymphocytes (CTLs) within
a tumour, assist the priming of tumour-specific CTLs in lymphoid organs and establish …
a tumour, assist the priming of tumour-specific CTLs in lymphoid organs and establish …
[HTML][HTML] Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression
M Qi, Y Xia, Y Wu, Z Zhang, X Wang, L Lu, C Dai… - Nature …, 2022 - nature.com
The formation of pre-metastatic niche is a key step in the metastatic burden. The pluripotent
factor Lin28B is frequently expressed in breast tumors and is particularly upregulated in the …
factor Lin28B is frequently expressed in breast tumors and is particularly upregulated in the …
[HTML][HTML] Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress
Radiation therapy can potentially induce immunogenic cell death, thereby priming anti-
tumor adaptive immune responses. However, radiation-induced systemic immune …
tumor adaptive immune responses. However, radiation-induced systemic immune …
[HTML][HTML] CTLA-4 in regulatory T cells for cancer immunotherapy
Simple Summary In the fight against cancer, immunotherapies have given great hope after
encouraging results in clinical investigations showing complete remission in some patients …
encouraging results in clinical investigations showing complete remission in some patients …
The inflammatory microenvironment and microbiome in prostate cancer development
Chronic inflammation promotes the development of several types of solid cancers and might
contribute to prostate carcinogenesis. This hypothesis partly originates in the frequent …
contribute to prostate carcinogenesis. This hypothesis partly originates in the frequent …
[HTML][HTML] The dark side of IFN-γ: its role in promoting cancer immunoevasion
M Mojic, K Takeda, Y Hayakawa - International journal of molecular …, 2017 - mdpi.com
Interferon-γ (IFN-γ) is a pleiotropic cytokine that has long been praised as an important
effector molecule of anti-tumor immunity, capable of suppressing tumor growth through …
effector molecule of anti-tumor immunity, capable of suppressing tumor growth through …
[HTML][HTML] Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response
Alterations in gut microbiota impact the pathophysiology of several diseases, including
cancer. Radiotherapy (RT), an established curative and palliative cancer treatment, exerts …
cancer. Radiotherapy (RT), an established curative and palliative cancer treatment, exerts …
[HTML][HTML] Antitumor effects of immunity-enhancing traditional Chinese medicine
Y Wang, Q Zhang, Y Chen, CL Liang, H Liu… - Biomedicine & …, 2020 - Elsevier
Abstract Traditional Chinese Medicine (TCM) has been traditionally used to treat patients
with cancers in China. It not only alleviates the symptoms of tumor patients and improves …
with cancers in China. It not only alleviates the symptoms of tumor patients and improves …
[HTML][HTML] Identification of a nine-gene signature and establishment of a prognostic nomogram predicting overall survival of pancreatic cancer
M Wu, X Li, T Zhang, Z Liu, Y Zhao - Frontiers in oncology, 2019 - frontiersin.org
Background: Pancreatic cancer is highly lethal and aggressive with increasing trend of
mortality in both genders. An effective prediction model is needed to assess prognosis of …
mortality in both genders. An effective prediction model is needed to assess prognosis of …