Lipid deposition and metabolism in local and modern pig breeds: A review

K Poklukar, M Čandek-Potokar, N Batorek Lukač… - Animals, 2020 - mdpi.com
Simple Summary Intensive selective breeding and genetic improvement of relatively few pig
breeds led to the abandonment of many low productive local pig breeds. However, local pig …

[HTML][HTML] Our emerging understanding of the roles of long non-coding RNAs in normal liver function, disease, and malignancy

A Mahpour, AC Mullen - JHEP Reports, 2021 - Elsevier
Long non-coding RNAs (lncRNAs) are important biological mediators that regulate
numerous cellular processes. New experimental evidence suggests that lncRNAs play …

Long non-coding RNA NEAT1 mediated RPRD1B stability facilitates fatty acid metabolism and lymph node metastasis via c-Jun/c-Fos/SREBP1 axis in gastric cancer

Y Jia, Q Yan, Y Zheng, L Li, B Zhang, Z Chang… - Journal of Experimental …, 2022 - Springer
Background Lymph node metastasis is one of most common determinants of the stage and
prognosis of gastric cancer (GC). However, the key molecular events and mechanisms …

The long noncoding RNA CHROME regulates cholesterol homeostasis in primates

EJ Hennessy, C van Solingen, KR Scacalossi… - Nature …, 2019 - nature.com
The human genome encodes thousands of long noncoding RNAs (lncRNAs), the majority of
which are poorly conserved and uncharacterized. Here we identify a primate-specific …

Long non‐coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes

H Wang, Y Cao, L Shu, Y Zhu, Q Peng… - Journal of cellular …, 2020 - Wiley Online Library
Liver plays an essential role in regulating lipid metabolism, and chronically disturbed
hepatic metabolism may cause obesity and metabolic syndrome, which may lead to non …

[HTML][HTML] Close interactions between lncRNAs, lipid metabolism and ferroptosis in cancer

J Huang, J Wang, H He, Z Huang, S Wu… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Abnormal lipid metabolism including synthesis, uptake, modification, degradation and
transport has been considered a hallmark of malignant tumors and contributes to the supply …

Long noncoding RNAs in lipid metabolism: literature review and conservation analysis across species

K Muret, C Désert, L Lagoutte, M Boutin, F Gondret… - BMC genomics, 2019 - Springer
Background Lipids are important for the cell and organism life since they are major
components of membranes, energy reserves and are also signal molecules. The main …

Long non-coding RNA CDKN2B-AS1 contributes to atherosclerotic plaque formation by forming RNA-DNA triplex in the CDKN2B promoter

M Ou, X Li, S Zhao, S Cui, J Tu - EBioMedicine, 2020 - thelancet.com
Background Atherosclerosis involves a slow process of plaque formation on the walls of
arteries, and comprises a leading cause of cardiovascular disease. Long non-coding RNAs …

Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study

Y Wang, MS Selvaraj, X Li, Z Li, JA Holdcraft… - The American Journal of …, 2023 - cell.com
Long non-coding RNAs (lncRNAs) are known to perform important regulatory functions in
lipid metabolism. Large-scale whole-genome sequencing (WGS) studies and new statistical …

The role of long noncoding RNA in lipid, cholesterol, and glucose metabolism and treatment of obesity syndrome

Q Lu, P Guo, A Liu, I Ares… - Medicinal research …, 2021 - Wiley Online Library
Obesity syndromes, characterized by abnormal lipid, cholesterol, and glucose metabolism,
are detrimental to human health and cause many diseases, including obesity and type II …