Endothelial injury and microvascular/macrovascular thrombosis are common
pathophysiological features of coronavirus disease-2019 (COVID-19). However, the optimal …

The Academic Research Consortium (ARC)-2 initiative revisited the clinical and
angiographic end point definitions in coronary device trials, proposed in 2007, to make them …

Background Severe tricuspid regurgitation is a debilitating condition that is associated with
substantial morbidity and often with poor quality of life. Decreasing tricuspid regurgitation …

Background The appropriate duration of dual antiplatelet therapy in patients at high risk for
bleeding after the implantation of a drug-eluting coronary stent remains unclear. Methods …

Abstract Aims The Valve Academic Research Consortium (VARC), founded in 2010, was
intended to (i) identify appropriate clinical endpoints and (ii) standardize definitions of these …

Background COVID-19 is associated with a prothrombotic state leading to adverse clinical
outcomes. Whether therapeutic anticoagulation improves outcomes in patients hospitalised …

Importance Thrombotic events are commonly reported in critically ill patients with COVID-19.
Limited data exist to guide the intensity of antithrombotic prophylaxis. Objective To evaluate …

Background Myocardial infarction is a frequent cause of out-of-hospital cardiac arrest.
However, the benefits of early coronary angiography and revascularization in resuscitated …

Background The benefit of complete revascularization in older patients (≥ 75 years of age)
with myocardial infarction and multivessel disease remains unclear. Methods In this …

Background: Percutaneous closure of the left atrial appendage (LAA) is an alternative to
chronic oral anticoagulation to reduce stroke risk in patients with nonvalvular atrial …