Portable nanopore-sequencing technology: Trends in development and applications
P Chen, Z Sun, J Wang, X Liu, Y Bai, J Chen… - Frontiers in …, 2023 - frontiersin.org
Sequencing technology is the most commonly used technology in molecular biology
research and an essential pillar for the development and applications of molecular biology …
research and an essential pillar for the development and applications of molecular biology …
Applications and potentials of nanopore sequencing in the (epi) genome and (epi) transcriptome era
Summary The Human Genome Project opened an era of (epi) genomic research, and also
provided a platform for the development of new sequencing technologies. During and after …
provided a platform for the development of new sequencing technologies. During and after …
Genpip: In-memory acceleration of genome analysis via tight integration of basecalling and read mapping
Nanopore sequencing is a widely-used high-throughput genome sequencing technology
that can sequence long fragments of a genome into raw electrical signals at low cost …
that can sequence long fragments of a genome into raw electrical signals at low cost …
Efficient end-to-end long-read sequence mapping using minimap2-fpga integrated with hardware accelerated chaining
Abstract minimap2 is the gold-standard software for reference-based sequence mapping in
third-generation long-read sequencing. While minimap2 is relatively fast, further speedup is …
third-generation long-read sequencing. While minimap2 is relatively fast, further speedup is …
Accelerating genome analysis via algorithm-architecture co-design
High-throughput sequencing (HTS) technologies have revolutionized the field of genomics,
enabling rapid and cost-effective genome analysis for various applications. However, the …
enabling rapid and cost-effective genome analysis for various applications. However, the …
Exponential function computation based on DNA strand displacement circuits
Y Wang, T Mao, J Sun, P Liu - IEEE Transactions on …, 2022 - ieeexplore.ieee.org
Due to its high programmability and storage, DNA circuits have been widely used in
biological computing. In this paper, the addition, subtraction, multiplication, division, n-order …
biological computing. In this paper, the addition, subtraction, multiplication, division, n-order …
Cross layer design using HW/SW co-design and HLS to accelerate chaining in genomic analysis
DNA sequence analysis is a computationally intensive task. Minimap2 is a state-of-the-art
software tool for third-generation sequence analysis workflow. Nearly 50% of Minimap2's …
software tool for third-generation sequence analysis workflow. Nearly 50% of Minimap2's …
A scalable discrete-time integrated CMOS readout array for nanopore based DNA sequencing
Y Dawji, M Habibi, E Ghafar-Zadeh… - IEEE Access, 2021 - ieeexplore.ieee.org
This paper introduces a high-speed mixed-signal readout array in 130-nm CMOS for the
amplification and digitization of picoampere-range signals. Its design is inspired by the …
amplification and digitization of picoampere-range signals. Its design is inspired by the …
RawHash: enabling fast and accurate real-time analysis of raw nanopore signals for large genomes
Nanopore sequencers generate electrical raw signals in real-time while sequencing long
genomic strands. These raw signals can be analyzed as they are generated, providing an …
genomic strands. These raw signals can be analyzed as they are generated, providing an …
Miniaturized DNA sequencers for personal use: Unreachable dreams or achievable goals
The appearance of next generation sequencing technology that features short read length
with high measurement throughput and low cost has revolutionized the field of life science …
with high measurement throughput and low cost has revolutionized the field of life science …