The evolution of HIV-1 and the origin of AIDS

PM Sharp, BH Hahn - … of the Royal Society B: Biological …, 2010 - royalsocietypublishing.org
The major cause of acquired immune deficiency syndrome (AIDS) is human
immunodeficiency virus type 1 (HIV-1). We have been using evolutionary comparisons to …

Tracking a century of global expansion and evolution of HIV to drive understanding and to combat disease

DM Tebit, EJ Arts - The Lancet infectious diseases, 2011 - thelancet.com
Since the isolation of HIV, multiple transmissions are thought to have occurred between man
and other old-world primates. Assessment of samples from apes and human beings with …

DAMBE5: a comprehensive software package for data analysis in molecular biology and evolution

X Xia - Molecular biology and evolution, 2013 - academic.oup.com
Since its first release in 2001 as mainly a software package for phylogenetic analysis, data
analysis for molecular biology and evolution (DAMBE) has gained many new functions that …

Human immunodeficiency virus (HIV)

GAC Blood - Transfusion Medicine and Hemotherapy, 2016 - karger.com
German Advisory Committee Blood (Arbeitskreis Blut), Subgroup 'Assessment of Pathogens
Transmissible by Blood'tein, TM) are derived. In addition to the structural proteins, the HIV …

[PDF][PDF] Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains

D Sauter, M Schindler, A Specht, WN Landford… - Cell host & …, 2009 - cell.com
Vpu proteins of pandemic HIV-1 M strains degrade the viral receptor CD4 and antagonize
human tetherin to promote viral release and replication. We show that Vpus from SIVgsn …

[HTML][HTML] Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2

B Jia, R Serra-Moreno, W Neidermyer Jr… - PLoS …, 2009 - journals.plos.org
Tetherin, also known as BST2, CD317 or HM1. 24, was recently identified as an interferon-
inducible host–cell factor that interferes with the detachment of virus particles from infected …

Hybrid origin of SIV in chimpanzees

E Bailes, F Gao, F Bibollet-Ruche, V Courgnaud… - Science, 2003 - science.org
The ancestry of HIV-1 (human immunodeficiency virus–1) has been traced to SIVcpz (simian
immunodeficiency virus) infecting chimpanzees (Pan troglodytes)] in west central Africa (1) …

[PDF][PDF] Nef proteins from simian immunodeficiency viruses are tetherin antagonists

F Zhang, SJ Wilson, WC Landford, B Virgen… - Cell host & …, 2009 - cell.com
Summary The tetherin/BST2/CD317 protein blocks the release of HIV-1 and other
enveloped viruses by inducing tethering of nascent particles to infected cell surfaces. The …

[HTML][HTML] HIV-1 Vpu promotes release and prevents endocytosis of nascent retrovirus particles from the plasma membrane

SJD Neil, SW Eastman, N Jouvenet… - PLoS …, 2006 - journals.plos.org
The human immunodeficiency virus (HIV) type-1 viral protein U (Vpu) protein enhances the
release of diverse retroviruses from human, but not monkey, cells and is thought to do so by …

[HTML][HTML] HIV-1 accessory protein Vpu internalizes cell-surface BST-2/tetherin through transmembrane interactions leading to lysosomes

Y Iwabu, H Fujita, M Kinomoto, K Kaneko… - Journal of Biological …, 2009 - ASBMB
Bone marrow stromal antigen 2 (BST-2, also known as tetherin) is a recently identified
interferon-inducible host restriction factor that can block the production of enveloped viruses …