Differences in the prevalence of chronic pain in women vs. men are well known, and
decades of laboratory experimentation have demonstrated that women are more sensitive to …

Studies have shown differences in specific cognitive ability domains and risk of Alzheimer's
disease between the men and women at later age. However it is important to know that sex …

Traumatic brain injury (TBI) remains one of the leading causes of mortality and morbidity
worldwide, yet despite extensive efforts to develop neuroprotective therapies for this …

Neurodegenerative diseases (NDs) are a wide class of disorders of the central nervous
system (CNS) with unknown etiology. Several factors were hypothesized to be involved in …

Traumatic brain injury (TBI) causes secondary biochemical changes that contribute to
subsequent tissue damage and associated neuronal cell death. Neuroprotective treatments …

Emerging data indicate that progesterone has multiple non-reproductive functions in the
central nervous system to regulate cognition, mood, inflammation, mitochondrial function …

In recent years there has been a growing body of clinical and laboratory evidence
demonstrating the neuroprotective effects of estrogen and progesterone after traumatic brain …

Despite substantial investments by government, philanthropic, and commercial sources over
the past several decades, traumatic brain injury (TBI) remains an unmet medical need and a …

Sex differences in neurological disease extend from incidence, severity, progression and
symptoms and may ultimately influence treatment. Cognitive disturbances are frequent in …

STUDY OBJECTIVE: Laboratory evidence indicates that progesterone has potent
neuroprotective effects. We conducted a pilot clinical trial to assess the safety and potential …