miRNA dosage control in development and human disease
In mammals, miRNAs recognize target mRNAs via base pairing, which leads to a complex
'multiple-to-multiple'regulatory network. Previous studies have focused on the regulatory …
'multiple-to-multiple'regulatory network. Previous studies have focused on the regulatory …
Lung cancer epigenetics: from knowledge to applications
M Duruisseaux, M Esteller - Seminars in cancer biology, 2018 - Elsevier
Lung cancer is the leading cause of cancer-related mortality worldwide. Advances in our
understanding of the genomics of lung cancer have led to substantial progress in the …
understanding of the genomics of lung cancer have led to substantial progress in the …
The immune landscape of cancer
We performed an extensive immunogenomic analysis of more than 10,000 tumors
comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across cancer …
comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across cancer …
CancerSEA: a cancer single-cell state atlas
H Yuan, M Yan, G Zhang, W Liu, C Deng… - Nucleic acids …, 2019 - academic.oup.com
High functional heterogeneity of cancer cells poses a major challenge for cancer research.
Single-cell sequencing technology provides an unprecedented opportunity to decipher …
Single-cell sequencing technology provides an unprecedented opportunity to decipher …
Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection
TA Wagner, S McLaughlin, K Garg, CYK Cheung… - Science, 2014 - science.org
Antiretroviral treatment (ART) of HIV infection suppresses viral replication. Yet if ART is
stopped, virus reemerges because of the persistence of infected cells. We evaluated the …
stopped, virus reemerges because of the persistence of infected cells. We evaluated the …
A systematic review of miR-29 in cancer
MicroRNAs (miRNA) are small non-coding RNAs (∼ 22 nt in length) that are known as
potent master regulators of eukaryotic gene expression. miRNAs have been shown to play a …
potent master regulators of eukaryotic gene expression. miRNAs have been shown to play a …
Competing endogenous RNA networks: tying the essential knots for cancer biology and therapeutics
A Sanchez-Mejias, Y Tay - Journal of hematology & oncology, 2015 - Springer
A recently discovered dimension of post-transcriptional gene regulation involves co-
regulatory crosstalk between RNA transcripts, which compete for common pools of …
regulatory crosstalk between RNA transcripts, which compete for common pools of …
Deep sequencing of RNA from three different extracellular vesicle (EV) subtypes released from the human LIM1863 colon cancer cell line uncovers distinct miRNA …
Secreted microRNAs (miRNAs) enclosed within extracellular vesicles (EVs) play a pivotal
role in intercellular communication by regulating recipient cell gene expression and affecting …
role in intercellular communication by regulating recipient cell gene expression and affecting …
[HTML][HTML] Comprehensive characterization of lncRNA-mRNA related ceRNA network across 12 major cancers
Recent studies indicate that long noncoding RNAs (lncRNAs) can act as competing
endogenous RNAs (ceRNAs) to indirectly regulate mRNAs through shared microRNAs …
endogenous RNAs (ceRNAs) to indirectly regulate mRNAs through shared microRNAs …
Diverse roles of miR-29 in cancer
H Jiang, G Zhang, JH Wu, CP Jiang - Oncology reports, 2014 - spandidos-publications.com
Abstract microRNAs (miRNAs) are non-coding RNAs which have the capacity to regulate
gene expression at the post-transcriptional level, and have emerging as key factors involved …
gene expression at the post-transcriptional level, and have emerging as key factors involved …