Advances in pluripotent stem cells: history, mechanisms, technologies, and applications

G Liu, BT David, M Trawczynski, RG Fessler - Stem cell reviews and …, 2020 - Springer
Over the past 20 years, and particularly in the last decade, significant developmental
milestones have driven basic, translational, and clinical advances in the field of stem cell …

Tissue engineering and regenerative medicine: achievements, future, and sustainability in Asia

F Han, J Wang, L Ding, Y Hu, W Li, Z Yuan… - … in bioengineering and …, 2020 - frontiersin.org
Exploring innovative solutions to improve the healthcare of the aging and diseased
population continues to be a global challenge. Among a number of strategies toward this …

Induced pluripotent stem cells: applications in regenerative medicine, disease modeling, and drug discovery

VK Singh, M Kalsan, N Kumar, A Saini… - Frontiers in cell and …, 2015 - frontiersin.org
Recent progresses in the field of Induced Pluripotent Stem Cells (iPSCs) have opened up
many gateways for the research in therapeutics. iPSCs are the cells which are …

The promise of induced pluripotent stem cells in research and therapy

DA Robinton, GQ Daley - Nature, 2012 - nature.com
The field of stem-cell biology has been catapulted forward by the startling development of
reprogramming technology. The ability to restore pluripotency to somatic cells through the …

Cancer stem cell hierarchy in glioblastoma multiforme

A Bradshaw, A Wickremsekera, ST Tan, L Peng… - Frontiers in …, 2016 - frontiersin.org
Glioblastoma multiforme (GBM), an aggressive tumor that typically exhibits treatment failure
with high mortality rates, is associated with the presence of cancer stem cells (CSCs) within …

The tumorigenicity of human embryonic and induced pluripotent stem cells

U Ben-David, N Benvenisty - Nature Reviews Cancer, 2011 - nature.com
The unique abilities of human pluripotent stem cells to self-renew and to differentiate into
cells of the three germ layers make them an invaluable tool for the future of regenerative …

A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts

R Li, J Liang, S Ni, T Zhou, X Qing, H Li, W He, J Chen… - Cell stem cell, 2010 - cell.com
Epithelial-to-mesenchymal transition (EMT) is a developmental process important for cell
fate determination. Fibroblasts, a product of EMT, can be reset into induced pluripotent stem …

Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins

D Kim, CH Kim, JI Moon, YG Chung, MY Chang… - Cell stem cell, 2009 - cell.com
To date, all methods to generate induced pluripotent stem cells (iPSCs) require the use of
genetic materials and/or potentially mutagenic molecules. Here we report the generation of …

[HTML][HTML] Generation of induced pluripotent stem cells using recombinant proteins

H Zhou, S Wu, JY Joo, S Zhu, DW Han, T Lin… - Cell stem cell, 2009 - cell.com
Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins: Cell Stem Cell Skip
to Main Content Advertisement Cell Stem Cell This journal offers authors two options (open …

Induced pluripotency: history, mechanisms, and applications

M Stadtfeld, K Hochedlinger - Genes & development, 2010 - genesdev.cshlp.org
The generation of induced pluripotent stem cells (iPSCs) from somatic cells demonstrated
that adult mammalian cells can be reprogrammed to a pluripotent state by the enforced …