Amplification-free CRISPR/Cas detection technology: challenges, strategies, and perspectives
Rapid and accurate molecular diagnosis is a prerequisite for precision medicine, food
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …
Testing at scale during the COVID-19 pandemic
Assembly and publication of the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome in January 2020 enabled the immediate development of tests to detect the …
CoV-2) genome in January 2020 enabled the immediate development of tests to detect the …
Wearable materials with embedded synthetic biology sensors for biomolecule detection
PQ Nguyen, LR Soenksen, NM Donghia… - Nature …, 2021 - nature.com
Integrating synthetic biology into wearables could expand opportunities for noninvasive
monitoring of physiological status, disease states and exposure to pathogens or toxins …
monitoring of physiological status, disease states and exposure to pathogens or toxins …
Fast and sensitive detection of SARS-CoV-2 RNA using suboptimal protospacer adjacent motifs for Cas12a
S Lu, X Tong, Y Han, K Zhang, Y Zhang… - Nature biomedical …, 2022 - nature.com
CRISPR-based assays for the detection of nucleic acids are highly specific, yet they are not
fast, sensitive or easy to use. Here we report a one-step fluorescence assay for the detection …
fast, sensitive or easy to use. Here we report a one-step fluorescence assay for the detection …
[HTML][HTML] Diverse functional autoantibodies in patients with COVID-19
COVID-19 manifests with a wide spectrum of clinical phenotypes that are characterized by
exaggerated and misdirected host immune responses,,,,–. Although pathological innate …
exaggerated and misdirected host immune responses,,,,–. Although pathological innate …
Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy
The December 2019 outbreak of a novel respiratory virus, SARS-CoV-2, has become an
ongoing global pandemic due in part to the challenge of identifying symptomatic …
ongoing global pandemic due in part to the challenge of identifying symptomatic …
COVID-19 diagnosis—A review of current methods
M Yüce, E Filiztekin, KG Özkaya - Biosensors and Bioelectronics, 2021 - Elsevier
A fast and accurate self-testing tool for COVID-19 diagnosis has become a prerequisite to
comprehend the exact number of cases worldwide and to take medical and governmental …
comprehend the exact number of cases worldwide and to take medical and governmental …
Measurement of SARS-CoV-2 RNA in wastewater tracks community infection dynamics
We measured severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA
concentrations in primary sewage sludge in the New Haven, Connecticut, USA, metropolitan …
concentrations in primary sewage sludge in the New Haven, Connecticut, USA, metropolitan …
Rapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection
Background Accurate rapid diagnostic tests for SARS‐CoV‐2 infection would be a useful
tool to help manage the COVID‐19 pandemic. Testing strategies that use rapid antigen tests …
tool to help manage the COVID‐19 pandemic. Testing strategies that use rapid antigen tests …
[HTML][HTML] Longitudinal analyses reveal immunological misfiring in severe COVID-19
Recent studies have provided insights into the pathogenesis of coronavirus disease 2019
(COVID-19),,–. However, the longitudinal immunological correlates of disease outcome …
(COVID-19),,–. However, the longitudinal immunological correlates of disease outcome …