Clustered miRNAs and their role in biological functions and diseases
MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …
The osteoporosis/microbiota linkage: the role of miRNA
M De Martinis, L Ginaldi, A Allegra, MM Sirufo… - International journal of …, 2020 - mdpi.com
Hundreds of trillions of bacteria are present in the human body in a mutually beneficial
symbiotic relationship with the host. A stable dynamic equilibrium exists in healthy …
symbiotic relationship with the host. A stable dynamic equilibrium exists in healthy …
MiR-497∼ 195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1α activity
M Yang, CJ Li, X Sun, Q Guo, Y Xiao, T Su… - Nature …, 2017 - nature.com
A specific bone vessel subtype, strongly positive for CD31 and endomucin (CD31hiEmcnhi),
is identified as coupling angiogenesis and osteogenesis. The abundance of type …
is identified as coupling angiogenesis and osteogenesis. The abundance of type …
[HTML][HTML] MiR-27a is essential for the shift from osteogenic differentiation to adipogenic differentiation of mesenchymal stem cells in postmenopausal osteoporosis
L You, L Pan, L Chen, W Gu, J Chen - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Osteoporosis is a progressive bone disease characterized by a decrease
in bone mass and density, which results in an increased risk of fractures. Mesenchymal stem …
in bone mass and density, which results in an increased risk of fractures. Mesenchymal stem …
The role of microRNAs in bone remodeling
Bone remodeling is balanced by bone formation and bone resorption as well as by
alterations in the quantities and functions of seed cells, leading to either the maintenance or …
alterations in the quantities and functions of seed cells, leading to either the maintenance or …
Circulating miR-181c-5p and miR-497-5p are potential biomarkers for prognosis and diagnosis of osteoporosis
J Ma, X Lin, C Chen, S Li, S Zhang… - The Journal of …, 2020 - academic.oup.com
Context Osteoporosis is a degenerative bone disease in aging men and women. MiRNAs
associated with progressive bone loss in osteoporosis had not been clearly demonstrated …
associated with progressive bone loss in osteoporosis had not been clearly demonstrated …
MicroRNAs and periodontal homeostasis
X Luan, X Zhou, J Trombetta-eSilva… - Journal of dental …, 2017 - journals.sagepub.com
MicroRNAs (miRNAs) are a group of small RNAs that control gene expression in all aspects
of eukaryotic life, primarily through RNA silencing mechanisms. The purpose of the present …
of eukaryotic life, primarily through RNA silencing mechanisms. The purpose of the present …
Functional role of circRNAs in osteogenesis: A review
The extracellular matrixes (ECM), as well as the microenvironmental signals, play an
essential role in osteogenesis by regulating intercellular pathways. Recently, it has been …
essential role in osteogenesis by regulating intercellular pathways. Recently, it has been …
MicroRNAs in bone diseases
L Gennari, S Bianciardi, D Merlotti - Osteoporosis International, 2017 - Springer
MicroRNAs are small, noncoding single-stranded RNAs that have emerged as important
posttranscriptional regulators of gene expression, with an essential role in vertebrate …
posttranscriptional regulators of gene expression, with an essential role in vertebrate …
Epigenetic regulation of bone remodeling and its impacts in osteoporosis
Epigenetics describes mechanisms which control gene expression and cellular processes
without changing the DNA sequence. The main mechanisms in epigenetics are DNA …
without changing the DNA sequence. The main mechanisms in epigenetics are DNA …