[HTML][HTML] Alcohol-induced liver injury in signalling pathways and curcumin's therapeutic potential

V Subramaniyan, NSA Lubau, N Mukerjee… - Toxicology Reports, 2023 - Elsevier
Confronting the profound public health concern of alcohol-induced liver damage calls for
inventive therapeutic measures. The social, economic, and clinical ramifications are …

Food antioxidants and aging: Theory, current evidence and perspectives

T Miyazawa, C Abe, GC Burdeos, A Matsumoto… - Nutraceuticals, 2022 - mdpi.com
The concept of food and aging is of great concern to humans. So far, more than 300 theories
of aging have been suggested, and approaches based on these principles have been …

Neuromodulatory effect of vardenafil on aluminium chloride/d-galactose induced Alzheimer's disease in rats: emphasis on amyloid-beta, p-tau, PI3K/Akt/p53 pathway …

HH Awad, MA Desouky, A Zidan, M Bassem… - …, 2023 - Springer
Dysregulation of protein homeostasis, proteostasis, is a distinctive hallmark of many
neurodegenerative disorders and aging. Deleteriously, the accumulation of aberrant …

Longevity Spinach (Gynura procumbens) Ameliorated Oxidative Stress and Inflammatory Mediators in Cisplatin‐Induced Organ Dysfunction in Rats: Comprehensive in vivo …

M Chandra Shill, HAS El‐Nashar… - Chemistry & …, 2024 - Wiley Online Library
This study focused to assess the efficacy of Gynura procumbens (GP) leaf extract against
cisplatin (CP)‐induced hepatorenal complications in Wister albino rats. Additionally, it aims …

Antiaging effects of dietary supplements and natural products

L Gao, X Liu, X Luo, X Lou, P Li, X Li… - Frontiers in Pharmacology, 2023 - frontiersin.org
Aging is an inevitable process influenced by genetics, lifestyles, and environments. With the
rapid social and economic development in recent decades, the proportion of the elderly has …

The synergistic effect of nanocurcumin and donepezil on Alzheimer's via PI3K/AKT/GSK-3β pathway modulating

DM Beltagy, NF Nawar, TM Mohamed… - Prostaglandins & Other …, 2024 - Elsevier
Alzheimer's disease (AD) hallmarks include amyloid-βeta (Aβ) and tau proteins aggregates,
neurite degeneration, microglial activation with cognitive impairment. Phosphatidylinositol-3 …

Combination of epigallocatechin 3 gallate and curcumin improves d-galactose and normal-aging associated memory impairment in mice

MA Rahman, AA Shuvo, MMH Apu, MR Bhakta… - Scientific Reports, 2023 - nature.com
Previously, we observed curcumin improves aging-associated memory impairment in d-
galactose (D-gal) and normal-aged (NA) mice. Evidence showed that multiple agents can be …

Protective Effect of Curcumin on D-Galactose-Induced Senescence and Oxidative Stress in LLC-PK1 and HK-2 Cells

SS García-Trejo, T Gómez-Sierra, D Eugenio-Pérez… - Antioxidants, 2024 - mdpi.com
D-galactose has been widely used as an inducer of cellular senescence and
pathophysiological processes related to aging because it induces oxidative stress. On the …

The neuroprotective and antioxidant effects of Nanocurcumin oral suspension against lipopolysaccharide-induced cortical neurotoxicity in rats

A Salah, M Yousef, M Kamel, A Hussein - Biomedicines, 2022 - mdpi.com
Lipopolysaccharide (LPS) proved to be an important tool, not only in the induction of
neuroinflammatory models, but also in demonstrating the behavioral and cognitive …

Nuclear factor erythrogen-2 associated factor 2 (Nrf2) signaling is an essential molecular pathway for the anti-aging effect of whey protein in the prefrontal cortex of …

NR Sarhan, EM El Nashar, E Hamza, SM El-Beah… - Tissue and Cell, 2023 - Elsevier
Aging is a highly complicated natural process. Brain aging is associated with remarkable
neurodegenerative changes and oxidative damage. Whey protein (WP) has been …