Decorin is an extracellular matrix protein that belongs to the family of small leucine‐rich
proteoglycans. As a matrix protein, the first discovered role of decorin is participating in …

Rationale: There is increasing evidence for the presence of autoantibodies in chronic
obstructive pulmonary disease (COPD). Chronic oxidative stress is an essential component …

Chronic obstructive pulmonary disease (COPD) is a major public health problem because of
its high prevalence, rising incidence and associated socio-economic cost. The inhalation of …

This invention relates to the identification of peptide binding to ligands, and in particular to
identification of epitopes expressed by microorganisms and by mammalian cells. The …

The role of autoimmune pathology in development and progression of chronic obstructive
pulmonary disease (COPD) is becoming increasingly appreciated. In this study, we …

Purpose: Non–small cell lung cancer (NSCLC) has an overall 5-year survival of< 15%;
however, the 5-year survival for stage I disease is over 50%. Unfortunately, 75% of NSCLC …

Objectives Autoantibodies tumor‐associated antigens (TAAs) could be a valuable tool for
the diagnosis or early detection of cancer due to their relatively high specificity and stability …

Background Autoantibodies against self-antigens have been associated not only with
autoimmune diseases, but also with cancer and are even found in healthy individuals. The …

Background Circulating antiendothelial cell antibodies (AECA) bind to endothelial antigens
and induce endothelial cell damage. These antibodies have been detected in patients with …

We assessed the autoantibody repertoire of a mouse model engineered to develop breast
cancer and the repertoire of autoantibodies in human plasmas collected at a preclinical time …