Role of human macrophage polarization in inflammation during infectious diseases

C Atri, FZ Guerfali, D Laouini - International journal of molecular sciences, 2018 - mdpi.com
Experimental models have often been at the origin of immunological paradigms such as the
M1/M2 dichotomy following macrophage polarization. However, this clear dichotomy in …

The roles of macrophage polarization in the host immune response to sepsis

X Chen, Y Liu, Y Gao, S Shou, Y Chai - International immunopharmacology, 2021 - Elsevier
Sepsis is a life-threatening clinical syndrome caused by infection. Its pathogenesis is
complex and entails coagulation dysfunction, inflammation, and immune disorders …

Microglial M1/M2 polarization and metabolic states

R Orihuela, CA McPherson… - British journal of …, 2016 - Wiley Online Library
Microglia are critical nervous system‐specific immune cells serving as tissue‐resident
macrophages influencing brain development, maintenance of the neural environment …

From monocytes to M1/M2 macrophages: phenotypical vs. functional differentiation

P Italiani, D Boraschi - Frontiers in immunology, 2014 - frontiersin.org
Studies on monocyte and macrophage biology and differentiation have revealed the
pleiotropic activities of these cells. Macrophages are tissue sentinels that maintain tissue …

Macrophage biology and mechanisms of immune suppression in breast cancer

AK Mehta, S Kadel, MG Townsend, M Oliwa… - Frontiers in …, 2021 - frontiersin.org
Macrophages are crucial innate immune cells that maintain tissue homeostasis and defend
against pathogens; however, their infiltration into tumors has been associated with adverse …

Automated single-cell proteomics providing sufficient proteome depth to study complex biology beyond cell type classifications

C Ctortecka, NM Clark, BW Boyle, A Seth… - Nature …, 2024 - nature.com
The recent technological and computational advances in mass spectrometry-based single-
cell proteomics have pushed the boundaries of sensitivity and throughput. However …

Bone marrow mesenchymal stem cell-derived small extracellular vesicles promote periodontal regeneration

L Liu, S Guo, W Shi, Q Liu, F Huo, Y Wu… - … Engineering Part A, 2021 - liebertpub.com
Bone marrow mesenchymal stem cell-derived small extracellular vesicles (BMSC-sEVs) can
be used as a potential cell-free strategy for periodontal tissue regeneration, and we aim to …

Enhanced activity of macrophage M1/M2 phenotypes in periodontitis

J Yang, Y Zhu, D Duan, P Wang, Y Xin, L Bai, Y Liu… - Archives of oral …, 2018 - Elsevier
Objective Monocytes/macrophages play a key role in mobilizing host defense against
microbial infection. The selectivity of gene expression can turn macrophages into M1-or M2 …

Macrophages in tumor: An inflammatory perspective

KK Goswami, A Bose, R Baral - Clinical Immunology, 2021 - Elsevier
Inflammation is a part of carefully co-ordinated healing immune exercise to eliminate
injurious stimuli. However, in substantial number of cancer types, it contributes in shaping up …

Single-cell profiling of Ebola virus disease in vivo reveals viral and host dynamics

D Kotliar, AE Lin, J Logue, TK Hughes, NM Khoury… - Cell, 2020 - cell.com
Ebola virus (EBOV) causes epidemics with high mortality yet remains understudied due to
the challenge of experimentation in high-containment and outbreak settings. Here, we used …