[HTML][HTML] Anticancer drug-induced cardiotoxicity: insights and pharmacogenetics

A Adhikari, SMB Asdaq, MA Al Hawaj, M Chakraborty… - Pharmaceuticals, 2021 - mdpi.com
The advancement in therapy has provided a dramatic improvement in the rate of recovery
among cancer patients. However, this improved survival is also associated with enhanced …

[HTML][HTML] The value of Genus Acacia in arid and semi-arid environments for the treatment of chronic inflammatory diseases

A Atiya, T Majrashi, S Akhtar, AA Khan, AMS Asiri… - Phytomedicine Plus, 2022 - Elsevier
Background Chronic inflammatory diseases, such as chronic respiratory diseases, stroke,
cardiovascular disease, cancer, diabetes and obesity, kill six out of every ten people in the …

The effect of curcumin nanoparticles on cisplatin-induced cardiotoxicity in male wistar albino rats

YA Khadrawy, EN Hosny, MM El-Gizawy… - Cardiovascular …, 2021 - Springer
The cardiotoxicity of chemotherapeutic drugs as cisplatin has become a major issue in
recent years. The present study investigates the efficacy of curcumin nanoparticles against …

[HTML][HTML] Acacia hydaspica R. Parker ethyl-acetate extract abrogates cisplatin-induced nephrotoxicity by targeting ROS and inflammatory cytokines

T Afsar, S Razak, D Aldisi, M Shabbir, A Almajwal… - Scientific Reports, 2021 - nature.com
Cisplatin (CisPT) is a chemotherapeutic drug that outcomes in adverse effects. In this study,
we examined the effect of A. hydaspica ethyl acetate extract (AHE) in an animal model of …

[HTML][HTML] Cardioprotective and Hepatoprotective Potential of Silymarin in Paracetamol-Induced Oxidative Stress

B Okiljević, N Martić, S Govedarica, B Andrejić Višnjić… - Pharmaceutics, 2024 - mdpi.com
Silymarin, derived from Silybum marianum, has been used in traditional medicine for various
ailments. In this study, the cardioprotective and hepatoprotective effects of silymarin against …

Clerodendrum volubile Ethanol Leaf Extract: A Potential Antidote to Doxorubicin‐Induced Cardiotoxicity in Rats

OE Olorundare, AA Adeneye, AO Akinsola… - Journal of …, 2020 - Wiley Online Library
Doxorubicin is widely applied in hematological and solid tumor treatment but limited by its off‐
target cardiotoxicity. Thus, cardioprotective potential and mechanism (s) of CVE in DOX …

The cardioprotective effect of human glucagon‐like peptide‐1 receptor agonist (semaglutide) on cisplatin‐induced cardiotoxicity in rats: Targeting mitochondrial …

MM Atef, YM Hafez, OS El‐Deeb… - Cell Biochemistry …, 2023 - Wiley Online Library
The cardiotoxic effect of chemotherapeutic agents as cisplatin has become a major issue
recently. Interference with mitochondrial dynamics, biogenesis, redox status, and apoptosis …

Silymarin: A promising cardioprotective agent

Z Zalat, N Kohaf, M Alm El-Din, H Elewa… - … and Medical Sciences, 2021 - journals.ekb.eg
Silymarin 'milk thistle'(Silybum marianum) plant, has been used for years for treatment of
different diseases such as liver and gallbladder disorders, protecting liver against snake bite …

Curcumin mitigates gentamicin induced-renal and cardiac toxicity via modulation of Keap1/Nrf2, NF-κB/iNOS and Bcl-2/BAX pathways

S Hamdy, GE Elshopakey, EF Risha, S Rezk… - Food and Chemical …, 2024 - Elsevier
Gentamicin (GEN) is an aminoglycoside antibiotic used to treat gram-negative bacterial
infections. Our study aimed to explore curcumin's (CMN) protective role against GEN …

Exploring the cardioprotective effects of canagliflozin against cisplatin‐induced cardiotoxicity: Role of iNOS/NF‐κB, Nrf2, and Bax/cytochrome C/Bcl‐2 signals

FEM Ali, EHM Hassanein… - … of Biochemical and …, 2023 - Wiley Online Library
Cardiotoxicity is a severe considerable side effect of cisplatin (CDDP) that requires much
medical attention. The current study investigates the cardioprotective effects of canagliflozin …