In vitro Analytical Techniques as Screening Tools to investigate the Metal chelate‐DNA interactions
N Varghese, JR Jose, PM Krishna, D Philip… - …, 2023 - Wiley Online Library
Deoxyribose nucleic acid (DNA) is found to be the most efficient pharmacological target of
many synthetic molecules which are deemed as potential drugs with clinical applications …
many synthetic molecules which are deemed as potential drugs with clinical applications …
[HTML][HTML] In silico evaluation of binding of 2-deoxy-D-glucose with Mpro of nCoV to combat COVID-19
COVID-19 has threatened the existence of humanity andthis infection occurs due to SARS-
CoV-2 or novel coronavirus, was first reported in Wuhan, China. Therefore, there is a need …
CoV-2 or novel coronavirus, was first reported in Wuhan, China. Therefore, there is a need …
Structural and electrochemical elucidation of biocatalytic mechanisms in direct electron transfer-type D-fructose dehydrogenase
E Fukawa, Y Suzuki, T Adachi, T Miyata, F Makino… - Electrochimica …, 2024 - Elsevier
D-Fructose dehydrogenase (FDH) from Gluconobacter japonicus NBRC3260, a membrane-
bound heterotrimeric flavohemoprotein capable of intense direct electron transfer (DET)-type …
bound heterotrimeric flavohemoprotein capable of intense direct electron transfer (DET)-type …
Potential alternatives to current cholinesterase inhibitors: an in silico drug repurposing approach
Acetylcholinesterase/Butyrylcholinesterase inhibitors are considered an effective method for
treating Alzheimer's disease (AD). In this current work, we have computationally analyzed 11 …
treating Alzheimer's disease (AD). In this current work, we have computationally analyzed 11 …
Crystal structure, Hirshfeld, computational biomolecular investigations, and MTT assay studies of amino pyrimidine derivative as EGFR kinase domain inhibitor
A nitrogen heterocyclic pyrimidine fused heterocyclic derivative 4-(4-Methoxyphenyl)-6-(2-
phenylethyl) pyrimidin-2-amine (MPPPA), was synthesized and crystal structure is identified …
phenylethyl) pyrimidin-2-amine (MPPPA), was synthesized and crystal structure is identified …
[HTML][HTML] Potent hepatoprotective activity of common rattan (Calamus rotang L.) leaf extract and its molecular mechanism
WS Anwar, FM Abdel-Maksoud, AM Sayed… - … medicine and therapies, 2023 - Springer
Abstract Background Calamus rotang L.(CR) is an Indian shrub. The leaves and other
organs of the plant are traditionally used in India for treatment of various diseases. The in …
organs of the plant are traditionally used in India for treatment of various diseases. The in …
Antimalarial activity of curcumin and kaempferol using structure-based drug design method
Malaria is a major global health problem caused by plasmodium parasites. The alarming
spread of drug resistance and its limited availability underscores the importance of …
spread of drug resistance and its limited availability underscores the importance of …
[HTML][HTML] Evaluation of Linkers' Influence on Peptide-Based Piezoelectric Biosensors' Sensitivity to Aldehydes in the Gas Phase
T Wasilewski, D Neubauer, M Wojciechowski… - International Journal of …, 2023 - mdpi.com
Recent findings qualified aldehydes as potential biomarkers for disease diagnosis. One of
the possibilities is to use electrochemical biosensors in point-of-care (PoC), but these need …
the possibilities is to use electrochemical biosensors in point-of-care (PoC), but these need …
Virtual screening reveals aprepitant to be a potent inhibitor of neutral sphingomyelinase 2: implications in blockade of exosome release in cancer therapy
Purpose Exosomes are membrane-derived nano-vesicles upregulated in pathological
conditions like cancer. Therefore, inhibiting their release is a potential strategy for the …
conditions like cancer. Therefore, inhibiting their release is a potential strategy for the …
Comparison of herbicide specificity of CYP81A cytochrome P450s from rice and a multiple‐herbicide resistant weed, Echinochloa phyllopogon
W Ha, T Yamaguchi, S Iwakami… - Pest Management …, 2022 - Wiley Online Library
Abstract BACKGROUND CYP81A cytochrome P450s (CYP81As) play a key role in
herbicide detoxification in Poaceae plants. Crop CYP81As confer natural tolerance to …
herbicide detoxification in Poaceae plants. Crop CYP81As confer natural tolerance to …