Immune mechanisms play an important role in the pathogenesis of glomerulonephritis (GN),
with autoimmunity being the main underlying pathogenetic process of both primary and …

Anti-glomerular basement membrane disease (Anti-GBM), previously known as
Goodpasture syndrome, is an extremely rare cause of rapidly progressive …

Autoantibodies play an important role in the pathophysiology of renal involvement in
systemic autoimmune diseases, such as systemic lupus erythematosus (SLE), systemic …

Retransplantation accounts for approximately 15% of the annual transplants performed in
the USA, and in the recent International Collaborative Transplant Study report on pediatric …

A young male patient with rapidly progressive and life-threatening pulmonary haemorrhage
due to anti-glomerular basement membrane (anti-GBM) antibody disease without renal …

Background Anti-glomerular basement membrane (GBM) antibody disease is a rare
autoimmune disorder characterized by rapidly progressive glomerulonephritis caused by …

Background Rapidly progressive glomerulonephritis (RPGN) is clinically manifestations as a
rapidly progressive renal failure and pathologically as crescentic and necrotizing lesions …

We report a case of 63-year-old Chinese man, having a history of anti-myeloperoxidase
(MPO) antibody anti-neutrophil cytoplasmic antibody (ANCA)-associated pulmonary-renal …

The major epitopes recognized by autoantibodies in anti-glomerular basement membrane
(GBM) disease are found in the α3-subunit non-collagenous domain of type IV collagen [α3 …

Interventions: The key to obtain a good prognosis was the early application of corticosteroids
and cyclophosphamide in combination with plasmapheresis to make the anti-GBM antibody …