Chalcones are a class of privileged scaffolds with high medicinal significance due to the
presence of an α, β-unsaturated ketone functionality. Numerous functional modifications of …

Chalcones, containing an α, β-unsaturated ketone fragment, are an important
pharmacologically active agents because of their diverse mechanisms. This review provides …

New antibacterial 3-(aminothiazolyl) quinolones (ATQs) were designed and efficiently
synthesized to counteract the growing multidrug resistance in animal husbandry. Bioactive …

A series of thiazol-4-one/thiophene-bearing pyrazole derivatives as pharmacologically
attractive cores were initially synthesized using a hybridization approach. All structures were …

The increasing incidence of microbial resistance and newly emerging pathogens have
become a serious challenge for public health. More and more efforts have been directed to …

Aminothiazolyl berberine derivatives as potentially antimicrobial agents were designed and
synthesized in an effort to overcome drug resistance. The antimicrobial assay revealed that …

This study aimed to synthesize new potent quinoline derivatives based on hydrazone
moieties and evaluate their antimicrobial activity. The newly synthesized hydrazono …

In the present study we designed and synthesized 26 coumarin clubbed chalcone hybrids (1–
13 and 14–26) in good yields (54.32–74.25%) and further tested for their antimicrobial and …

Compounds bearing thiazole and chalcone pharmacophores have been reported to
possess excellent antitubercular and anticancer activities. In view of this, we designed …

A series of chalcone analogues (1–15) were synthesized by Claisen-Schmidt condensation
in good yields (70–95%) and characterized by FT-IR, 1 H NMR and mass spectral methods …