The freeze-drying of foods—The characteristic of the process course and the effect of its parameters on the physical properties of food materials

D Nowak, E Jakubczyk - Foods, 2020 - mdpi.com
Freeze-drying, also known as lyophilization, is a process in which water in the form of ice
under low pressure is removed from a material by sublimation. This process has found many …

Biopolymer based nanomaterials in drug delivery systems: A review

J Jacob, JT Haponiuk, S Thomas, S Gopi - Materials today chemistry, 2018 - Elsevier
Drug delivery systems (DDS) are used to achieve a higher therapeutic effects of a
pharmaceutical drug or natural compound in a specific diseased site with minimal …

[HTML][HTML] Dry powder for pulmonary delivery: A comprehensive review

B Chaurasiya, YY Zhao - Pharmaceutics, 2021 - mdpi.com
The pulmonary route has long been used for drug administration for both local and systemic
treatment. It possesses several advantages, which can be categorized into physiological, ie …

Physical stability of dry powder inhaler formulations

N Shetty, D Cipolla, H Park, QT Zhou - Expert opinion on drug …, 2020 - Taylor & Francis
ABSTRACT Introduction: Dry powder inhalers (DPIs) are popular for pulmonary drug
delivery. Various techniques have been employed to produce inhalation drug particles and …

Spray freeze drying: Emerging applications in drug delivery

DA Vishali, J Monisha, SK Sivakamasundari… - Journal of Controlled …, 2019 - Elsevier
Spray freeze drying is relatively a recent drying technique involving heterogeneous set of
steps which includes droplet formation, freezing, and sublimation. It has proven benefits over …

Aerosolizable siRNA-encapsulated solid lipid nanoparticles prepared by thin-film freeze-drying for potential pulmonary delivery

JL Wang, MS Hanafy, H Xu, J Leal, Y Zhai… - International Journal of …, 2021 - Elsevier
Lipid nanoparticles are increasingly used for drug and gene delivery, including the delivery
of small interfering RNA (siRNA). Pulmonary delivery of drug molecules carried by lipid …

Dry powder pharmaceutical biologics for inhalation therapy

RYK Chang, MYT Chow, D Khanal, D Chen… - Advanced Drug Delivery …, 2021 - Elsevier
Therapeutic biologics such as genes, peptides, proteins, virus and cells provide clinical
benefits and are becoming increasingly important tools in respiratory medicine. Pulmonary …

Spray freeze-drying as a solution to continuous manufacturing of pharmaceutical products in bulk

MB Adali, AA Barresi, G Boccardo, R Pisano - Processes, 2020 - mdpi.com
Pharmaceutical manufacturing is evolving from traditional batch processes to continuous
ones. The new global competition focused on throughput and quality of drug products is …

Particle engineering principles and technologies for pharmaceutical biologics

D Cun, C Zhang, H Bera, M Yang - Advanced Drug Delivery Reviews, 2021 - Elsevier
The global market of pharmaceutical biologics has expanded significantly during the last few
decades. Currently, pharmaceutical biologic products constitute an indispensable part of the …

A comparative study of encapsulation of carotenoid enriched-flaxseed oil and flaxseed oil by spray freeze-drying and spray drying techniques

A Elik, DK Yanık, F Göğüş - Lwt, 2021 - Elsevier
Encapsulation of carotenoid enriched flaxseed oil was performed by spray freeze-drying by
using sixteen different emulsion formulations. Emulsions, which contain various …