Mendelian and complex genetic trait diseases continue to burden and affect society both
socially and economically. The lack of effective tests has hampered diagnosis thus, the …

Here, we describe single-tube long fragment read (stLFR), a technology that enables
sequencing of data from long DNA molecules using economical second-generation …

Background More extensive use of metagenomic shotgun sequencing in microbiome
research relies on the development of high-throughput, cost-effective sequencing. Here we …

Sepsis is a systemic inflammatory response syndrome caused by infection, resulting in
organ dysfunction. Sepsis‐induced acute kidney injury (AKI) is one of the most common …

Ancient DNA research has been revolutionized following development of next-generation
sequencing platforms. Although a number of such platforms have been applied to ancient …

Aging is a key risk factor for chronic diseases of the elderly. MicroRNAs regulate post-
transcriptional gene silencing through base-pair binding on their target mRNAs. We …

The development and innovation of next generation sequencing (NGS) and the subsequent
analysis tools have gain popularity in scientific researches and clinical diagnostic …

Breast cancer is a heterogeneous disease with distinct molecular subtypes including the
aggressive subtype triple-negative breast cancer (TNBC). We compared blood-borne …

The reduction in the red to far-red light ratio (R/FR) and photosynthetically active radiation
caused by dense planting initiates shade avoidance responses (SARs) to help plants …

Single-cell RNA-seq technologies require library preparation prior to sequencing. Here, we
present the first report to compare the cheaper BGISEQ-500 platform to the Illumina HiSeq …