Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found
throughout the cell that lack protein‐coding function. Their functions are closely linked to …

Background: Long-non-coding RNAs (lncRNAs), RNA molecules longer than 200
nucleotides, have been involved in several biological processes and in a growing number of …

Long non-coding RNAs (lncRNA), a class of non-coding RNA molecules recently identified
largely due to the efforts of FANTOM, and later GENCODE and ENCODE consortia, have …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the main cause
of dementia among the elderly worldwide. Despite intense efforts to develop drugs for …

mRNA stability influences gene expression and translation in almost all living organisms,
and the levels of mRNA molecules in the cell are determined by a balance between …

Only a small fraction of the human genome corresponds to protein-coding genes.
Historically, the vast majority of genomic sequence was dismissed as transcriptionally silent …

BACE1 is the rate-limiting enzyme for amyloid-β peptides (Aβ) generation, a key event in the
pathogenesis of Alzheimer's disease (AD). By an unknown mechanism, levels of BACE1 …

The human genome is pervasively transcribed, producing a majority of short and long
noncoding RNAs (lncRNAs) that can influence cellular programs through a variety of …

The underlying genetic variations of late-onset Alzheimer's disease (LOAD) cases remain
largely unknown. A combination of genetic variations with variable penetrance and lifetime …

Long noncoding RNAs (lncRNAs) are transcripts with low protein-coding potential but
occupy a large part of transcriptional output. Their roles include regulating gene expression …