SLAM modification as an immune-modulatory therapeutic approach in cancer

A Tojjari, FJ Giles, M Vilbert, A Saeed, L Cavalcante - Cancers, 2023 - mdpi.com
Simple Summary In the dynamic realm of cancer research, the Signaling Lymphocyte
Activation Molecule (SLAM) family has emerged as a significant factor in modulating …

[HTML][HTML] Exploring TSGA10 Function: A Crosstalk or Controlling Mechanism in the Signaling Pathway of Carcinogenesis?

F Taghizadeh-Hesary, M Ghadyani, F Kashanchi… - Cancers, 2024 - mdpi.com
Simple Summary This research aims to explore the role of the TSGA10 protein in cancer
development, specifically in how it might influence the growth and spread of cancer cells …

CYP26A1 Links WNT and Retinoic Acid Signaling: A Target to Differentiate ALDH+ Stem Cells in APC-Mutant CRC

COB Facey, VO Hunsu, C Zhang, B Osmond… - Cancers, 2024 - mdpi.com
Simple Summary This manuscript reports the discovery of a mechanism that links two major
cellular pathways, retinoic acid (RA) and WNT signaling, which are involved in colorectal …

From Crypts to Cancer: A Holistic Perspective on Colorectal Carcinogenesis and Therapeutic Strategies

E Gharib, GA Robichaud - International Journal of Molecular Sciences, 2024 - mdpi.com
Colorectal cancer (CRC) represents a significant global health burden, with high incidence
and mortality rates worldwide. Recent progress in research highlights the distinct clinical …

Malignant Melanoma: Insights into Cancer Stem Cells, Tumor Microenvironment, and the Renin-Angiotensin System

EJ Kilmister, ST Tan - 2024 - preprints.org
Malignant melanoma (MM) is the most fatal form of skin cancer, accounting for 90% of all
skin cancer deaths. Multiple dysregulated cellular pathways are involved in MM, including …

[HTML][HTML] Cancer stem cells in drug resistance: an introduction to the e-book covering the special issue on the “Cancer Stem Cells and Drug Resistance”

B Sarkadi - Cancer Drug Resistance, 2023 - ncbi.nlm.nih.gov
A major problem in current cancer drug treatment is that a subset of cancer cells in many
cases survives even highly efficient chemotherapy, and after a while, these remaining cells …

Understanding prostate cancer stem cells: implications for therapy and treatment resistance.

AK Flores-Islas, C Rico-Fuentes… - Boletin del Colegio …, 2023 - search.ebscohost.com
El cáncer de próstata (CaP) es una neoplasia maligna altamente heterogénea y de rápido
progreso con una etiología compleja. La presencia de células madre cancerosas (CSC) …

[PDF][PDF] Normal Cell Differentiation Potential of Cancer Stem Cells Without Reprogramming Pluripotent Factors: a Novel Strategy in Stem Cell-Based Therapy for Tissue …

JJ Alloysius - ijcsejournal.org
Stem cells hold great promise for tissue regeneration and have the potential to treat many
incurable degenerative diseases. Cancer stem cells (CSCs), or cancer initiating cells, have …